Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.44 |
| ▸ | GAA | P10253 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | SLC16A3 | O15427 | 2/20 | 0.42 |
| ▸ | SLC16A1 | P53985 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 10/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7064653 | 0.87 | ALDH1A1 (0.51) | ALDH1A1KDM4EGAAPOLBSLC16A3 | |
| SCHEMBL20339317 | 0.85 | ALDH1A1 (0.50) | ALDH1A1KDM4EGAAPOLBSLC16A3 | |
| SCHEMBL11939789 | 0.84 | ATG4B (0.46) | ALDH1A1KDM4EGAAPOLBSLC16A3 | |
| SCHEMBL10010371 | 0.83 | ALDH1A1 (0.56) | ALDH1A1POLBSLC16A3SLC16A1RAB9A | |
| SCHEMBL10010368 | 0.83 | ALDH1A1 (0.56) | ALDH1A1POLBSLC16A3SLC16A1RAB9A | |
| SCHEMBL11858448 | 0.83 | ALDH1A1 (0.51) | ALDH1A1KDM4EGAAPOLBSLC16A3 | |
| SCHEMBL8378029 | 0.83 | SLC16A3 (0.49) | ALDH1A1KDM4EGAAPOLBSLC16A3 | |
| SCHEMBL11692994 | 0.82 | ALDH1A1 (0.45) | ALDH1A1KDM4EGAAPOLBSLC16A3 | |
| SCHEMBL11939410 | 0.82 | ALDH1A1 (0.47) | ALDH1A1KDM4EGAAPOLBSLC16A3 | |
| SCHEMBL10853212 | 0.81 | SLC16A3 (0.48) | ALDH1A1KDM4EGAAPOLBSLC16A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120172599-A1 | SECOND-ORDER NONLINEAR OPTICAL COMPOUND AND NONLINEAR OPTICAL ELEMENT COMPRISING THE SAME | SUMITOMO ELECTRIC INDUSTRIES, LTD. (JP) | 2012-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120172599-A1 | SECOND-ORDER NONLINEAR OPTICAL COMPOUND AND NONLINEAR OPTICAL ELEMENT COMPRISING THE SAME | OGFOD1, OCIAD2, OCIAD1 | ALDH1A1 1660/4885KDM4E 2838/4885GAA 4234/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.