Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | SLC16A3 | O15427 | 2/20 | 0.37 |
| ▸ | SLC16A1 | P53985 | 2/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 2/20 | 0.36 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.35 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.33 |
| ▸ | FLT3 | P36888 | 2/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.33 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.33 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28277466 | 0.95 | BACE1 (0.43) | BACE1HDAC8C5AR1FLT3PTGER1 | |
| SCHEMBL11934280 | 0.94 | BACE1 (0.44) | BACE1SLC16A3SLC16A1HDAC8APP | |
| SCHEMBL10010017 | 0.94 | BACE1 (0.46) | BACE1SLC16A3SLC16A1HDAC8APP | |
| SCHEMBL10010014 | 0.94 | BACE1 (0.46) | BACE1SLC16A3SLC16A1HDAC8APP | |
| SCHEMBL12837173 | 0.86 | BACE1 (0.43) | BACE1SLC16A3SLC16A1HDAC8APP | |
| SCHEMBL11934282 | 0.86 | BACE1 (0.45) | BACE1SLC16A3SLC16A1HDAC8APP | |
| SCHEMBL10010288 | 0.86 | BACE1 (0.45) | BACE1SLC16A3SLC16A1HDAC8APP | |
| SCHEMBL10010378 | 0.84 | BACE1 (0.37) | BACE1SLC16A3SLC16A1HDAC8ATG4B | |
| SCHEMBL10011228 | 0.84 | BACE1 (0.37) | BACE1SLC16A3SLC16A1HDAC8ATG4B | |
| SCHEMBL12837175 | 0.83 | LMNA (0.41) | SLC16A3SLC16A1APPATG4BALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120172599-A1 | SECOND-ORDER NONLINEAR OPTICAL COMPOUND AND NONLINEAR OPTICAL ELEMENT COMPRISING THE SAME | SUMITOMO ELECTRIC INDUSTRIES, LTD. (JP) | 2012-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120172599-A1 | SECOND-ORDER NONLINEAR OPTICAL COMPOUND AND NONLINEAR OPTICAL ELEMENT COMPRISING THE SAME | OGFOD1, OCIAD2, OCIAD1 | BACE1 4124/4885SLC16A3 3538/4885SLC16A1 4423/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.