Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 6/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | PIM1 | P11309 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CTSS | P25774 | 3/20 | 0.48 |
| ▸ | XDH | P47989 | 1/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.47 |
| ▸ | CTSK | P43235 | 5/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | IL4 | P05112 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.43 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.43 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11942096 | 0.91 | CTSS (0.51) | ADORA1MEN1KMT2APIM1L3MBTL1 | |
| SCHEMBL11940988 | 0.90 | ADORA1 (0.50) | ADORA1MEN1KMT2APIM1L3MBTL1 | |
| SCHEMBL28452160 | 0.89 | ADORA1 (0.70) | ADORA1MEN1KMT2APIM1L3MBTL1 | |
| SCHEMBL11937163 | 0.87 | ADORA1 (0.47) | ADORA1MEN1KMT2APIM1L3MBTL1 | |
| SCHEMBL11937158 | 0.85 | ADORA1 (0.64) | ADORA1MEN1KMT2APIM1L3MBTL1 | |
| SCHEMBL11942095 | 0.85 | CTSS (0.47) | ADORA1MEN1KMT2APIM1L3MBTL1 | |
| SCHEMBL14290491 | 0.83 | ADORA1 (0.56) | ADORA1MEN1KMT2APIM1L3MBTL1 | |
| SCHEMBL3052342 | 0.83 | ADORA1 (0.60) | ADORA1MEN1KMT2APIM1L3MBTL1 | |
| SCHEMBL11937165 | 0.82 | CTSS (0.44) | ADORA1MEN1KMT2APIM1L3MBTL1 | |
| SCHEMBL13098519 | 0.78 | ADORA1 (0.56) | ADORA1MEN1KMT2APIM1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120277252-A1 | Antibacterial Agents and Methods of Use Thereof | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2012-11-01 | — | — | US | disclosed |
| US-8227616-B2 | Cyanopyridine antibacterial agents and methods of use thereof | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2012-07-24 | — | — | US | disclosed |
| US-20100261763-A1 | ANTIBACTERIAL AGENTS AND METHODS OF USE THEREOF | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2010-10-14 | — | — | US | disclosed |
| US-7737164-B2 | Cyanopyridine antibacterial agents | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2010-06-15 | — | — | US | disclosed |
| WO-2008016738-A2 | ANTIBACTERIAL AGENTS AND RELATED SCREENING METHODS USING SMALL MOLECULE MACROARRAYS | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2008-02-07 | — | — | WO | disclosed |
| US-20080009528-A1 | ANTIBACTERIAL AGENTS AND RELATED SCREENING METHODS USING SMALL MOLECULE MACROARRAYS | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2008-01-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120277252-A1 | Antibacterial Agents and Methods of Use Thereof | FDPS, ABCG2, DUT | ADORA1 3317/4885MEN1 3582/4885KMT2A 4034/4885 |
| US-20080009528-A1 | ANTIBACTERIAL AGENTS AND RELATED SCREENING METHODS USING SMALL MOLECULE MACROARRAYS | PCNA, ABCG2, API5 | ADORA1 3358/4885MEN1 3709/4885KMT2A 3806/4885 |
| US-20100261763-A1 | ANTIBACTERIAL AGENTS AND METHODS OF USE THEREOF | FDPS, CYP3A5, ABCG2 | ADORA1 3520/4885MEN1 3578/4885KMT2A 3947/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.