SCHEMBL11941275

SCHEMBL11941275

N#C/C(=C\C=C(c1ccc(N(c2ccc(-c3ccccc3)cc2)c2ccc(-c3ccccc3)cc2)cc1)c1ccc(N(c2ccc(-c3ccccc3)cc2)c2ccc(-c3ccccc3)cc2)cc1)C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.49
SLC16A3 O15427 1/20 0.44
SLC16A1 P53985 1/20 0.44
APP P05067 1/20 0.42
ALDH1A1 P00352 2/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
HPGD P15428 1/20 0.37
SMN1; SMN2 Q16637 2/20 0.36
L3MBTL1 Q9Y468 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11941574 0.85 MAPT (0.48) MAPTSLC16A3SLC16A1APPALDH1A1
SCHEMBL4857575 0.82 KMT2A (0.44) MAPTSLC16A3SLC16A1ALDH1A1MEN1
SCHEMBL2807530 0.82 KMT2A (0.44) MAPTSLC16A3SLC16A1ALDH1A1MEN1
SCHEMBL2807525 0.82 KMT2A (0.44) MAPTSLC16A3SLC16A1ALDH1A1MEN1
SCHEMBL11941715 0.80 MCL1 (0.55) MAPTSLC16A3SLC16A1APPALDH1A1
SCHEMBL11940664 0.79 MAPT (0.58) MAPTSLC16A3SLC16A1ALDH1A1HPGD
SCHEMBL14191468 0.79 MAPT (0.58) MAPTSLC16A3SLC16A1ALDH1A1HPGD
SCHEMBL12673125 0.79 MAPT (0.58) MAPTSLC16A3SLC16A1ALDH1A1HPGD
SCHEMBL11941716 0.78 APP (0.52) MAPTSLC16A3SLC16A1APPALDH1A1
SCHEMBL11936970 0.78 MAPT (0.64) MAPTSLC16A3SLC16A1APPALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8227690-B2 Dye-sensitized photoelectric conversion device NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2012-07-24 US disclosed