Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | PKM | P14618 | 3/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.43 |
| ▸ | EGFR | P00533 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.43 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.43 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.43 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2807525 | 1.00 | KMT2A (0.44) | KMT2AALDH1A1KDM4EPKMATM | |
| SCHEMBL2807530 | 1.00 | KMT2A (0.44) | KMT2AALDH1A1KDM4EPKMATM | |
| SCHEMBL11941275 | 0.82 | MAPT (0.49) | KMT2AALDH1A1HPGDSLC16A3SLC16A1 | |
| SCHEMBL1576724 | 0.82 | POLB (0.46) | KMT2AALDH1A1KDM4EPKMATM | |
| SCHEMBL1576722 | 0.82 | POLB (0.46) | KMT2AALDH1A1KDM4EPKMATM | |
| SCHEMBL14163400 | 0.80 | DNM1 (0.46) | KMT2AALDH1A1KDM4EPKMATM | |
| SCHEMBL17466006 | 0.78 | MAPT (0.52) | KMT2AALDH1A1KDM4EATMLMNA | |
| SCHEMBL11941574 | 0.77 | MAPT (0.48) | KMT2AALDH1A1HPGDSLC16A3SLC16A1 | |
| SCHEMBL11435558 | 0.76 | NFE2L2 (0.53) | KMT2AALDH1A1KDM4EPKMATM | |
| SCHEMBL11435556 | 0.76 | NFE2L2 (0.53) | KMT2AALDH1A1KDM4EPKMATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1535947-B1 | Diorganosiloxane derivatives containing a 4,4-diarylbutadiene moiety, sunscreen compositions containing them and their uses | OREAL (FR) | 2010-01-06 | — | — | EP | disclosed |
| US-7432386-B2 | Diarylbutadiene-substituted methyltrialkylsilanes and photoprotective compositions comprised thereof | L'OREAL (FR) | 2008-10-07 | — | — | US | disclosed |
| US-20070213547-A1 | For UV-photoprotecting human skin against the damaging effects of UV-radiation, notably UV-A radiation; example: monotrimethylsilanylmethyl monoethyl diester of (3,3-diphenyl-2-propylidene)propanedioic acid; good resistance to water and to perspiration | L'OREAL | 2007-09-13 | — | — | US | disclosed |
| US-7229609-B2 | Diarylbutadiene-substituted methyltrialkylsilanes and photoprotective compositions comprised thereof | L'OREAL (FR) | 2007-06-12 | — | — | US | disclosed |
| US-20050201957-A1 | Diarylbutadiene-substituted methyltrialkylsilanes and photoprotective compositions comprised thereof | L'OREAL (FR) | 2005-09-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070213547-A1 | For UV-photoprotecting human skin against the damaging effects of UV-radiation, notably UV-A radiation; example: monotrimethylsilanylmethyl monoethyl diester of (3,3-diphenyl-2-propylidene)propanedioic acid; good resistance to water and to perspiration | CUTA, DDB1, DCLRE1A | KMT2A 2767/4885ALDH1A1 109/4885KDM4E 1149/4885 |
| US-20050201957-A1 | Diarylbutadiene-substituted methyltrialkylsilanes and photoprotective compositions comprised thereof | MGMT, DDB1, ERCC1 | KMT2A 793/4885ALDH1A1 333/4885KDM4E 216/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.