Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 11/20 | 0.56 |
| ▸ | ACACA | Q13085 | 11/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | FPR2 | P25090 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | WEE1 | P30291 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16490009 | 1.00 | ACACB (0.56) | ACACBACACATHRBFPR2MAPT | |
| SCHEMBL14704798 | 0.90 | ACACB (0.56) | ACACBACACATHRBCA1CA2 | |
| SCHEMBL12458437 | 0.89 | ACACB (0.53) | ACACBACACATHRBFPR2 | |
| SCHEMBL14689609 | 0.89 | ACACB (0.53) | ACACBACACATHRBFPR2 | |
| SCHEMBL14689611 | 0.89 | ACACB (0.53) | ACACBACACATHRBFPR2 | |
| SCHEMBL14432172 | 0.87 | ACACB (0.50) | ACACBACACATHRBFPR2 | |
| SCHEMBL12841315 | 0.86 | ACACB (0.59) | ACACBACACATHRBMAPTCA1 | |
| SCHEMBL13596570 | 0.86 | ACACB (0.59) | ACACBACACATHRBCA1CA2 | |
| SCHEMBL30057496 | 0.86 | ACACB (0.70) | ACACBACACATHRBCA1CA2 | |
| SCHEMBL13174171 | 0.86 | ACACB (0.59) | ACACBACACATHRBMAPTCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170000143-A1 | A METHOD OF INDUCING RIPENESS IN FRUIT | BAYER CROPSCIENCE AG (DE) | 2017-01-05 | — | — | US | disclosed |
| US-9272997-B2 | Process for the preparation of 1-H-pyrrolidine-2,4-dione derivatives | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-03-01 | — | — | US | disclosed |
| US-20140371468-A1 | Process for the Preparation of 1-H-pyrrolidine-2,4-dione Derivatives | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2014-12-18 | — | — | US | disclosed |
| US-8859782-B2 | Process for the preparation of 1-H-pyrrolidine-2,4-dione derivatives | BAYER CROPSCIENCE AG (DE) | 2014-10-14 | — | — | US | disclosed |
| US-20120190865-A1 | Process for the Preparation of 1-H-pyrrolidine-2,4-dione Derivatives | BAYER CROPSCIENCE AG (DE) | 2012-07-26 | — | — | US | disclosed |
| EP-1277734-B1 | 2- and 2,5-substituted phenylketo-enols | BAYER CROPSCIENCE AG (DE) | 2007-02-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120190865-A1 | Process for the Preparation of 1-H-pyrrolidine-2,4-dione Derivatives | DHPS, HPD, DOHH | ACACB 4094/4885ACACA 4346/4885THRB 4427/4885 |
| US-20140371468-A1 | Process for the Preparation of 1-H-pyrrolidine-2,4-dione Derivatives | DHPS, HPD, DOHH | ACACB 4094/4885ACACA 4346/4885THRB 4427/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.