Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28297076 | 1.00 | HSD17B10 (0.61) | HSD17B10POLBMAPK1L3MBTL1NPSR1 | |
| SCHEMBL17706711 | 0.85 | HSD17B10 (0.43) | HSD17B10POLBMAPK1L3MBTL1NPSR1 | |
| SCHEMBL8562008 | 0.85 | HSD17B10 (0.43) | HSD17B10POLBMAPK1L3MBTL1NPSR1 | |
| SCHEMBL11713448 | 0.85 | HSD17B10 (0.43) | HSD17B10POLBMAPK1L3MBTL1NPSR1 | |
| SCHEMBL7096628 | 0.85 | HSD17B10 (0.58) | HSD17B10POLBMAPK1L3MBTL1NPSR1 | |
| SCHEMBL22407265 | 0.83 | L3MBTL1 (0.47) | HSD17B10POLBMAPK1L3MBTL1NPSR1 | |
| SCHEMBL31532972 | 0.81 | L3MBTL1 (0.41) | HSD17B10POLBMAPK1L3MBTL1NPSR1 | |
| SCHEMBL28094720 | 0.81 | HSD17B10 (0.50) | HSD17B10POLBMAPK1L3MBTL1NPSR1 | |
| SCHEMBL24550941 | 0.80 | HSD17B10 (0.53) | HSD17B10POLBMAPK1L3MBTL1NPSR1 | |
| SCHEMBL997678 | 0.80 | HSD17B10 (0.53) | HSD17B10POLBMAPK1L3MBTL1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7887835-B2 | for vascular lesion imaging and for diagnosing arteriosclerosis, ischemia with X-ray angiography and positron emission tomography; fluorinated steroid ester, glyceride compounds, phosphatidylcholine, and phosphatidylserine as membrane components of liposome | FUJIFILM CORPORATION (JP) | 2011-02-15 | — | — | US | disclosed |
| US-20080138285-A1 | Compound comprising a fluorine-substituted alkyl group and a liposome contrast medium comprising the compound | FUJIFILM CORPORATION (JP) | 2008-06-12 | — | — | US | disclosed |
| EP-1916255-A2 | Compound comprising a fluorine-substituted alkyl group and a liposome contrast medium comprising the compound | FUJIFILM Corporation (JP) | 2008-04-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080138285-A1 | Compound comprising a fluorine-substituted alkyl group and a liposome contrast medium comprising the compound | PHOSPHO1, SGMS1, SGMS2 | HSD17B10 1097/4885POLB 3865/4885MAPK1 1217/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.