Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CACNB4 | O00305 | 3/20 | 0.39 |
| ▸ | CACNA1A | O00555 | 3/20 | 0.39 |
| ▸ | CACNA1G | O43497 | 3/20 | 0.39 |
| ▸ | CACNG3 | O60359 | 3/20 | 0.39 |
| ▸ | CACNA1F | O60840 | 3/20 | 0.39 |
| ▸ | CACNA1H | O95180 | 3/20 | 0.39 |
| ▸ | CACNB3 | P54284 | 3/20 | 0.39 |
| ▸ | CACNA2D1 | P54289 | 3/20 | 0.39 |
| ▸ | CACNG7 | P62955 | 3/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.39 |
| ▸ | CACNA1D | Q01668 | 3/20 | 0.39 |
| ▸ | CACNB1 | Q02641 | 3/20 | 0.39 |
| ▸ | CACNG1 | Q06432 | 3/20 | 0.39 |
| ▸ | CACNB2 | Q08289 | 3/20 | 0.39 |
| ▸ | CACNA1S | Q13698 | 3/20 | 0.39 |
| ▸ | CACNA1C | Q13936 | 3/20 | 0.39 |
| ▸ | CACNA1E | Q15878 | 3/20 | 0.39 |
| ▸ | CACNA2D4 | Q7Z3S7 | 3/20 | 0.39 |
| ▸ | CACNA2D3 | Q8IZS8 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11944591 | 0.91 | MAPT (0.38) | MAPTCACNB4CACNA1ACACNA1GCACNG3 | |
| SCHEMBL11944981 | 0.87 | MCHR1 (0.41) | MAPTCACNB4CACNA1ACACNA1GCACNG3 | |
| SCHEMBL11944442 | 0.86 | CACNB4 (0.38) | MAPTCACNB4CACNA1ACACNA1GCACNG3 | |
| SCHEMBL11944456 | 0.86 | NPBWR1 (0.42) | MAPTCACNB4CACNA1ACACNA1GCACNG3 | |
| SCHEMBL11944101 | 0.85 | ALDH1A1 (0.51) | MAPTCACNB4CACNA1ACACNA1GCACNG3 | |
| SCHEMBL11944589 | 0.85 | CACNB4 (0.37) | MAPTCACNB4CACNA1ACACNA1GCACNG3 | |
| SCHEMBL11945061 | 0.84 | ALDH1A1 (0.50) | MAPTCACNB4CACNA1ACACNA1GCACNG3 | |
| SCHEMBL11945178 | 0.83 | POLB (0.39) | MAPTCACNB4CACNA1ACACNA1GCACNG3 | |
| SCHEMBL11944902 | 0.83 | MCHR1 (0.53) | MAPTALDH1A1DCTPP1MCHR1NPBWR1 | |
| SCHEMBL11944452 | 0.83 | MAPT (0.40) | MAPTCACNB4CACNA1ACACNA1GCACNG3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8232274-B2 | Pyridazinone derivatives useful as glucan synthase inhibitors | ALBANY MOLECULAR RESEARCH, INC. (US) | 2012-07-31 | — | — | US | disclosed |
| US-8232274-B2 | Pyridazinone derivatives useful as glucan synthase inhibitors | ALBANY MOLECULAR RESEARCH, INC. (US) | 2012-07-31 | — | — | US | disclosed |
| US-20090170861-A1 | Pyridazinone Derivatives Useful as Glucan Synthase Inhibitors | SCHERING CORPORATION AND ALBANY MOLECULAR RESEARCH, INC. | 2009-07-02 | — | — | US | disclosed |
| US-20090170861-A1 | Pyridazinone Derivatives Useful as Glucan Synthase Inhibitors | SCHERING CORPORATION AND ALBANY MOLECULAR RESEARCH, INC. | 2009-07-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090170861-A1 | Pyridazinone Derivatives Useful as Glucan Synthase Inhibitors | MAN2A1, GYS2, MANBA | MAPT 2295/4885CACNB4 4858/4885CACNA1A 4330/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.