Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.46 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CDC7 | O00311 | 1/20 | 0.41 |
| ▸ | PLK4 | O00444 | 1/20 | 0.41 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.41 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.41 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31144897 | 0.82 | ALDH1A1 (0.56) | ALDH1A1HPGDTDP1TSHRGRM2 | |
| SCHEMBL10888984 | 0.81 | HPGD (0.55) | ALDH1A1HPGDTDP1TSHRGRM2 | |
| SCHEMBL435010 | 0.78 | KDM4E (0.54) | ALDH1A1HPGDTSHRGRM2SLC9A1 | |
| SCHEMBL1233545 | 0.75 | TSHR (0.50) | ALDH1A1HPGDTDP1TSHRPOLB | |
| SCHEMBL18006020 | 0.74 | ALDH1A1 (1.00) | ALDH1A1HPGDTDP1TSHRGRM2 | |
| SCHEMBL5277049 | 0.73 | MAOA (0.38) | ALDH1A1HPGDTDP1GRM2SLC9A1 | |
| SCHEMBL3666291 | 0.71 | CDC7 (0.53) | ALDH1A1HPGDTDP1TSHRGRM2 | |
| SCHEMBL4352982 | 0.71 | TSHR (0.51) | ALDH1A1HPGDTDP1TSHRPOLB | |
| SCHEMBL4355668 | 0.71 | TSHR (0.73) | ALDH1A1HPGDTSHRPOLBKDM4E | |
| SCHEMBL795210 | 0.71 | HPGD (0.68) | HPGDTSHRPOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2350202-B1 | AZO DYES FOR DYEING AND PRINTING HYDROPHOBIC MATERIALS | DYSTAR COLOURS DISTRIB GMBH (DE) | 2014-01-15 | — | — | EP | disclosed |
| EP-2125962-B1 | DISPERSION DYE, THE PRODUCTION AND USE THEREOF | DYSTAR COLOURS DISTRIB GMBH (DE) | 2013-05-22 | — | — | EP | disclosed |
| US-8231691-B2 | Azo dyes | HUNTSMAN INTERNATIONAL LLC (US) | 2012-07-31 | — | — | US | disclosed |
| US-8231691-B2 | Azo dyes | HUNTSMAN INTERNATIONAL LLC (US) | 2012-07-31 | — | — | US | disclosed |
| US-8070832-B2 | Disperse dyes, their preparation and use | DYSTAR COLOURS DEUTSCHLAND GMBH (DE) | 2011-12-06 | — | — | US | disclosed |
| US-8070832-B2 | Disperse dyes, their preparation and use | DYSTAR COLOURS DEUTSCHLAND GMBH (DE) | 2011-12-06 | — | — | US | disclosed |
| EP-2254951-B1 | DISPERSE DYES, THEIR PREPARATION AND USE | DYSTAR COLOURS DEUTSCHLAND (DE) | 2011-10-19 | — | — | EP | disclosed |
| US-20110247150-A1 | DISPERSE DYES, THEIR PREPARATION AND USE | DYSTAR COLOURS DEUTSCHLANDS GMBH (DE) | 2011-10-13 | — | — | US | disclosed |
| US-20110247150-A1 | DISPERSE DYES, THEIR PREPARATION AND USE | DYSTAR COLOURS DEUTSCHLANDS GMBH (DE) | 2011-10-13 | — | — | US | disclosed |
| US-7909891-B2 | Azo dyes for dyeing and printing hydrophobic materials | DYSTAR COLOURS DEUTSCHLAND GMBH (DE) | 2011-03-22 | — | — | US | disclosed |
| US-20100281629-A1 | AZO DYES FOR DYEING AND PRINTING HYDROPHOBIC MATERIALS | DyStar Colours Deustschland GmbH (DE) | 2010-11-11 | — | — | US | disclosed |
| US-20100281629-A1 | AZO DYES FOR DYEING AND PRINTING HYDROPHOBIC MATERIALS | DyStar Colours Deustschland GmbH (DE) | 2010-11-11 | — | — | US | disclosed |
| US-20100196676-A1 | AZO DYES | HUNTSMAN INTERNATIONAL LLC (US) | 2010-08-05 | — | — | US | disclosed |
| US-20100196676-A1 | AZO DYES | HUNTSMAN INTERNATIONAL LLC (US) | 2010-08-05 | — | — | US | disclosed |
| US-20100076182-A1 | DISPERSION DYE, THE PRODUCTION AND USE THEREOF | DYSTAR COLOURS DISTRIBUTION GMBH (DE) | 2010-03-25 | — | — | US | disclosed |
| US-20100076182-A1 | DISPERSION DYE, THE PRODUCTION AND USE THEREOF | DYSTAR COLOURS DISTRIBUTION GMBH (DE) | 2010-03-25 | — | — | US | disclosed |
| WO-2009037215-A2 | AZO DYES FOR DYEING AND PRINTING HYDROPHOBIC MATERIALS | DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) | 2009-03-26 | — | — | WO | disclosed |
| WO-2009019207-A1 | DISPERSE DYES, THEIR PREPARATION AND USE | DYSTAR TEXTILFARBEN GMBH & CO DEUTSCHLAND KG (DE) | 2009-02-12 | — | — | WO | disclosed |
| WO-2009013122-A2 | AZO DYES | HUNTSMAN ADVANCED MATERIALS (SWITZERLAND) GMBH (CH) | 2009-01-29 | — | — | WO | disclosed |
| WO-2008090042-A1 | DISPERSION DYE, THE PRODUCTION AND USE THEREOF | DYSTAR TEXTILFARBEN GMBH & CO DEUTSCHLAND KG (DE) | 2008-07-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100281629-A1 | AZO DYES FOR DYEING AND PRINTING HYDROPHOBIC MATERIALS | H1-3, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, H1-4 | ALDH1A1 1742/4885HPGD 956/4885TDP1 2570/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.