Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 8/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.44 |
| ▸ | PRCP | P42785 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4397745 | 0.88 | PRCP (0.42) | OPRM1OPRK1PRCPTSHRNPSR1 | |
| SCHEMBL11948857 | 0.82 | PRCP (0.55) | OPRM1OPRK1PRCPGAAMAOA | |
| SCHEMBL11948844 | 0.80 | PRCP (0.46) | OPRM1OPRK1PRCPGAAMAOA | |
| SCHEMBL6986104 | 0.79 | PRCP (0.52) | PRCPTSHRNPSR1GAAMEN1 | |
| SCHEMBL11948845 | 0.78 | GID4 (0.56) | OPRM1OPRK1PRCPGAAMEN1 | |
| SCHEMBL11948841 | 0.76 | PRCP (0.47) | OPRM1OPRK1PRCPGAAMEN1 | |
| SCHEMBL11948846 | 0.72 | GID4 (0.57) | OPRM1OPRK1PRCPGAAMEN1 | |
| SCHEMBL11948842 | 0.71 | MAPT (0.42) | OPRM1PRCPTSHRNPSR1GAA | |
| SCHEMBL11948847 | 0.69 | PRCP (0.50) | PRCPGAAMEN1KMT2AMAOA | |
| SCHEMBL27859079 | 0.69 | PRCP (0.58) | OPRM1OPRK1PRCPTSHRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8232399-B2 | Chiral ligands, their preparation and uses thereof in asymmetric reactions | Li, Chao-Jun (CA) | 2012-07-31 | — | — | US | disclosed |