Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.56 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 2/20 | 0.49 |
| ▸ | HRH1 | P35367 | 1/20 | 0.49 |
| ▸ | PRCP | P42785 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11948846 | 0.92 | GID4 (0.57) | GID4MAOAHTR2AHRH1PRCP | |
| SCHEMBL4396321 | 0.87 | GID4 (0.55) | GID4MAOAHTR2AHRH1PRCP | |
| SCHEMBL11948857 | 0.85 | PRCP (0.55) | GID4MAOAPRCPRECQLGAA | |
| SCHEMBL11948844 | 0.83 | PRCP (0.46) | GID4MAOAHTR2APRCPRECQL | |
| SCHEMBL6986104 | 0.82 | PRCP (0.52) | GID4MAOAHTR2APRCPRECQL | |
| SCHEMBL4390310 | 0.79 | GID4 (0.56) | GID4MAOAHTR2APRCPRECQL | |
| SCHEMBL8406048 | 0.78 | GID4 (0.55) | GID4MAOAHTR2AHRH1PRCP | |
| SCHEMBL11948843 | 0.78 | OPRM1 (0.44) | GID4MAOAPRCPGAAOPRM1 | |
| SCHEMBL11948841 | 0.77 | PRCP (0.47) | GID4MAOAHTR2APRCPRECQL | |
| SCHEMBL11948848 | 0.76 | GID4 (0.49) | GID4MAOAPRCPRECQLGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8232399-B2 | Chiral ligands, their preparation and uses thereof in asymmetric reactions | Li, Chao-Jun (CA) | 2012-07-31 | — | — | US | disclosed |