Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.37 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.36 |
| ▸ | TSPO | P30536 | 1/20 | 0.35 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.35 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.34 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.34 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.34 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11949393 | 0.90 | MRGPRX4 (0.43) | KDM4ESMN1; SMN2MEN1KMT2AADAMTS4 | |
| SCHEMBL11949391 | 0.90 | ABCG2 (0.43) | KDM4ESMN1; SMN2MEN1KMT2AABCG2 | |
| SCHEMBL11949298 | 0.87 | STAT3 (0.40) | ADAMTS4MRGPRX4CYP2C19S1PR1 | |
| SCHEMBL14973183 | 0.84 | CA2 (0.49) | KDM4ESMN1; SMN2MEN1KMT2AADAMTS4 | |
| SCHEMBL14973073 | 0.78 | CA1 (0.44) | KDM4ESMN1; SMN2MEN1KMT2AMRGPRX4 | |
| SCHEMBL11949415 | 0.76 | HDAC4 (0.41) | KDM4EMEN1KMT2AADAMTS4MRGPRX4 | |
| SCHEMBL11949435 | 0.76 | HDAC6 (0.42) | S1PR1 | |
| SCHEMBL15150652 | 0.75 | GABRA5 (0.39) | KDM4EMRGPRX4POLBRAB9AGABRA5 | |
| SCHEMBL14972940 | 0.74 | CA2 (0.47) | KDM4ESMN1; SMN2MEN1KMT2AABCG2 | |
| SCHEMBL11948291 | 0.74 | STAT3 (0.36) | KDM4EMRGPRX4RAB9AGABRA5S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012099200-A1 | PYRAZOLE DERIVATIVE | 大正製薬株式会社 (JP) | 2012-07-26 | — | — | WO | disclosed |