Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MPI | P34949 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.40 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28539802 | 0.87 | KDM4E (0.51) | KDM4EMEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL1195261 | 0.84 | MEN1 (0.57) | KDM4EMEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL11351560 | 0.83 | AKR1C3 (0.44) | KDM4EMEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL28328296 | 0.81 | ALOX5 (0.52) | KDM4EMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL29506855 | 0.79 | KDM4E (0.60) | KDM4EMEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL929603 | 0.79 | ALDH1A1 (0.60) | KDM4EMEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL43510 | 0.79 | KDM4E (0.60) | KDM4EMEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL11363544 | 0.79 | ALDH1A1 (0.47) | KDM4EMEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL8834901 | 0.79 | NPC1 (0.54) | KDM4EMEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL4896934 | 0.78 | ALDH1A1 (0.84) | KDM4EMEN1KMT2AALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3946480-A1 | TWO-COMPONENT SYSTEM FOR THE THERAPEUTIC TREATMENT OF SKIN LESIONS AND PRODUCTION METHOD THEREOF | DTech - Società a Responsabilità Limitata (IT) | 2022-02-09 | — | — | EP | claimed |
| WO-2020201940-A1 | TWO-COMPONENT SYSTEM FOR THE THERAPEUTIC TREATMENT OF SKIN LESIONS AND PRODUCTION METHOD THEREOF | DTECH - SOCIETÀ A RESPONSABILITÀ LIMITATA (IT) | 2020-10-08 | — | — | WO | claimed |
| EP-0550006-B1 | Use of N-acyl derivatives of aminoalcohols for the manufacture of a medicament for the treatment of pathologies involving mast cells | LIFEGROUP SPA (IT) | 1999-09-08 | — | — | EP | claimed |
| EP-0751947-B1 | GLUCOSIDIC DERIVATIVES OF N-ACYL ALKYLAMINES EXERTING NEUROPROTECTIVE, NEUROTROPHIC AND ANTI-INFLAMMATORY ACTION, USEFUL IN ACUTE AND CHRONIC DISORDERS OF THE CENTRAL NERVOUS SYSTEM CONNECTED WITH EXCITOTOXICITY | LIFEGROUP SPA (IT) | 1998-08-12 | — | — | EP | claimed |
| US-5506224-A | ADMINISTERING TO TREAT MAMMALIAN PATHOLOGIES INVOLVING MAST CELL DEGRANULATION AS CONSEQUENCE OF NEUROGENIC AND/OR IMMUNOGENIC HYPERSTIMULATION | LIFEGROUP S.P.A. (IT) | 1996-04-09 | — | — | US | claimed |
| EP-0550006-A2 | Use of N-acyl derivatives of aminoalcohols for the manufacture of a medicament for the treatment of pathologies involving mast cells | LIFEGROUP S.p.A. (IT) | 1993-07-07 | — | — | EP | claimed |
| EP-0325061-A2 | Process for producing poly (para-phenylene-sulfide) | Tosoh Corporation (JP) | 1989-07-26 | — | — | EP | claimed |
| US-5506224-A | ADMINISTERING TO TREAT MAMMALIAN PATHOLOGIES INVOLVING MAST CELL DEGRANULATION AS CONSEQUENCE OF NEUROGENIC AND/OR IMMUNOGENIC HYPERSTIMULATION | LIFEGROUP S.P.A. (IT) | 1996-04-09 | — | — | US | disclosed |
| US-4542183-A | Fatigue crack growth retardant material | LOCKHEED CORPORATION (US) | 1985-09-17 | — | — | US | disclosed |