Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 5/20 | 0.40 |
| ▸ | PPARG | P37231 | 4/20 | 0.40 |
| ▸ | BACE1 | P56817 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 2/20 | 0.39 |
| ▸ | CTSS | P25774 | 4/20 | 0.39 |
| ▸ | CTSK | P43235 | 2/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10254703 | 0.91 | CTSS (0.50) | BACE1KDM4EALDH1A1MAPTCTSS | |
| SCHEMBL11953250 | 0.87 | CNR1 (0.41) | CNR1PPARACTSSCTSKCTSL | |
| SCHEMBL4103832 | 0.86 | CNR1 (0.48) | CNR1CYP2D6NR3C1TSHRHSD17B10 | |
| SCHEMBL13040292 | 0.85 | CTSS (0.41) | CNR1PPARAKDM4EALDH1A1MAPT | |
| SCHEMBL11953236 | 0.85 | CTSS (0.41) | CNR1PPARAPPARGCTSSCTSK | |
| SCHEMBL12902822 | 0.84 | REN (0.44) | CNR1CTSSCTSKCTSLCTSB | |
| SCHEMBL10255551 | 0.84 | CTSS (0.39) | CNR1PPARAPPARGCTSSCTSK | |
| SCHEMBL10255746 | 0.84 | HDAC4 (0.43) | CNR1CTSSCTSKCYP2D6TSHR | |
| SCHEMBL11953240 | 0.84 | CNR1 (0.41) | CNR1PPARACTSSCTSKCTSL | |
| SCHEMBL11965052 | 0.83 | CNR1 (0.44) | CNR1CYP2D6NR3C1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120196933-A1 | MEXILETINE PRODRUGS | FRANKLIN RICHARD (GB) | 2012-08-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120196933-A1 | MEXILETINE PRODRUGS | SLC16A1, MTPN, SLC16A3 | CNR1 745/4885PPARA 2997/4885PPARG 2616/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.