Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 7/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TYMP | P19971 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | FYN | P06241 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | AHR | P35869 | 2/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26634699 | 0.82 | CYP1A2 (0.47) | CYP1A2CYP2A6ALDH1A1HSD17B10HPGD | |
| SCHEMBL14217624 | 0.77 | SMN1; SMN2 (0.50) | CYP1A2ALDH1A1HPGDHIF1AAHR | |
| SCHEMBL13425164 | 0.76 | CYP1A2 (0.41) | CYP1A2CYP2A6ALDH1A1HSD17B10HPGD | |
| SCHEMBL20682620 | 0.76 | ALDH1A1 (0.43) | CYP1A2CYP2A6ALDH1A1HSD17B10HPGD | |
| SCHEMBL14144361 | 0.75 | CYP1A2 (0.40) | CYP1A2CYP2A6ALDH1A1HSD17B10HPGD | |
| SCHEMBL10109864 | 0.75 | HNF4A (0.45) | CYP1A2CYP2A6ALDH1A1HSD17B10HPGD | |
| SCHEMBL16283913 | 0.73 | TDP1 (0.45) | CYP1A2CYP2A6ALDH1A1HSD17B10HPGD | |
| SCHEMBL8516001 | 0.73 | CYP1A2 (0.41) | CYP1A2CYP2A6ALDH1A1HSD17B10HPGD | |
| SCHEMBL2847420 | 0.73 | CYP1A2 (0.38) | CYP1A2CYP2A6ALDH1A1HSD17B10HPGD | |
| SCHEMBL25592948 | 0.71 | CYP1A2 (0.40) | CYP1A2CYP2A6ALDH1A1HSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2886533-A1 | Use of Organophosphorus compounds based on tetraphenol (TP)-substituted structures | Evonik Degussa GmbH (DE) | 2015-06-24 | — | — | EP | disclosed |
| US-9000220-B2 | Organophosphorus compounds based on tetraphenol (TP)-substituted structures | EVONIK DEGUSSA GMBH (DE) | 2015-04-07 | — | — | US | disclosed |
| US-9000220-B2 | Organophosphorus compounds based on tetraphenol (TP)-substituted structures | EVONIK DEGUSSA GMBH (DE) | 2015-04-07 | — | — | US | disclosed |
| US-20120197025-A1 | ORGANOPHOSPHORUS COMPOUNDS BASED ON TETRAPHENOL (TP)-SUBSTITUTED STRUCTURES | EVONIK OXENO GMBH (DE) | 2012-08-02 | — | — | US | disclosed |
| US-20120197025-A1 | ORGANOPHOSPHORUS COMPOUNDS BASED ON TETRAPHENOL (TP)-SUBSTITUTED STRUCTURES | EVONIK OXENO GMBH (DE) | 2012-08-02 | — | — | US | disclosed |
| WO-2011023756-A2 | ORGANOPHOSPHORUS COMPOUNDS BASED ON TETRAPHENOL (TP)-SUBSTITUTED STRUCTURES | EVONIK OXENO GMBH (DE) | 2011-03-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120197025-A1 | ORGANOPHOSPHORUS COMPOUNDS BASED ON TETRAPHENOL (TP)-SUBSTITUTED STRUCTURES | PTMS, HPD, INPPL1 | CYP1A2 1276/4885CYP2A6 1712/4885ALDH1A1 4709/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.