Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12287122 | 0.84 | ALDH1A1 (0.39) | LMNAALDH1A1 | |
| SCHEMBL16615781 | 0.84 | DNM1 (0.36) | LMNA | |
| SCHEMBL16615645 | 0.84 | DNM1 (0.36) | LMNA | |
| SCHEMBL2735119 | 0.84 | LMNA (0.33) | LMNA | |
| SCHEMBL25970008 | 0.79 | — | — | |
| SCHEMBL2759867 | 0.79 | — | — | |
| SCHEMBL16079426 | 0.79 | — | — | |
| SCHEMBL26932464 | 0.78 | LMNA (0.35) | LMNAALDH1A1 | |
| SCHEMBL5961085 | 0.78 | LMNA (0.35) | LMNAALDH1A1 | |
| SCHEMBL3450776 | 0.78 | LMNA (0.35) | LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8232273-B2 | Heterocyclic compounds and methods of use | GENENTECH, INC. (US) | 2012-07-31 | — | — | US | disclosed |
| US-20100210622-A1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE | ABBVIE INC. | 2010-08-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100210622-A1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE | BCL2A1, BAX, BCL2 | LMNA 97/4885ALDH1A1 3017/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.