Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.61 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.61 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.61 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.61 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.61 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.61 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.61 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.61 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.61 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.61 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.61 |
| ▸ | GSK3B | P49841 | 1/20 | 0.61 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.61 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | CES2 | O00748 | 1/20 | 0.55 |
| ▸ | CES1 | P23141 | 1/20 | 0.55 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL459470 | 0.94 | KMT2A (0.70) | KMT2AHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL11052292 | 0.92 | MAPT (0.58) | KMT2APARP10MAPTNPC1RAB9A | |
| Butane SCHEMBL10982980 | 0.90 | KMT2A (0.66) | KMT2AHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL7859470 | 0.89 | KMT2A (0.64) | KMT2AHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL9607439 | 0.85 | KMT2A (0.74) | KMT2AHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL1269735 | 0.85 | ERCC5 (0.64) | HDAC3PARP10MAPTNPC1RAB9A | |
| SCHEMBL6061938 | 0.85 | PARP10 (0.58) | KMT2APARP10MAPTNPC1RAB9A | |
| SCHEMBL7139570 | 0.84 | KMT2A (0.59) | KMT2AHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL2773360 | 0.83 | GSK3B (0.89) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL6142684 | 0.83 | SRD5A2 (0.53) | KMT2AHDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120197407-A1 | HIGHLY LUBRICATING SLIDING MEMBER AND ARTIFICAL JOINT USING SAME | THE UNIVERSITY OF TOKYO (JP) | 2012-08-02 | — | — | US | disclosed |
| US-20120197407-A1 | HIGHLY LUBRICATING SLIDING MEMBER AND ARTIFICAL JOINT USING SAME | THE UNIVERSITY OF TOKYO (JP) | 2012-08-02 | — | — | US | disclosed |