SCHEMBL459470

SCHEMBL459470

CCC(=O)c1ccc(OC)cc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.70
HDAC3 O15379 3/20 0.68
HDAC4 P56524 3/20 0.68
HDAC1 Q13547 3/20 0.68
HDAC7 Q8WUI4 3/20 0.68
HDAC2 Q92769 3/20 0.68
HDAC10 Q969S8 3/20 0.68
HDAC11 Q96DB2 3/20 0.68
HDAC8 Q9BY41 3/20 0.68
HDAC6 Q9UBN7 3/20 0.68
HDAC9 Q9UKV0 3/20 0.68
HDAC5 Q9UQL6 3/20 0.68
GSK3B P49841 1/20 0.68
NR1I2 O75469 1/20 0.63
CES2 O00748 1/20 0.61
CES1 P23141 1/20 0.61
MAPT P10636 1/20 0.61
PDE4B Q07343 1/20 0.59
CA1 P00915 3/20 0.59
CA2 P00918 3/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Butane SCHEMBL10982980 0.96 KMT2A (0.66) KMT2AHDAC3HDAC4HDAC1HDAC7
SCHEMBL11955348 0.94 KMT2A (0.64) KMT2AHDAC3HDAC4HDAC1HDAC7
SCHEMBL7859470 0.94 KMT2A (0.64) KMT2AHDAC3HDAC4HDAC1HDAC7
SCHEMBL9607439 0.91 KMT2A (0.74) KMT2AHDAC3HDAC4HDAC1HDAC7
SCHEMBL7139570 0.89 KMT2A (0.59) KMT2AHDAC3HDAC4HDAC1HDAC7
SCHEMBL2099619 0.86 RAB9A (0.78) KMT2AMAPTNPC1RAB9AALDH1A1
SCHEMBL23039965 0.86 KMT2A (0.55) KMT2AHDAC3HDAC4HDAC1HDAC7
SCHEMBL11052292 0.84 MAPT (0.58) KMT2AMAPTNPC1RAB9AALDH1A1
SCHEMBL153386 0.84 ALDH1A1 (0.76) KMT2AHDAC3HDAC4HDAC1HDAC7
SCHEMBL16552644 0.84 MMP1 (0.76) KMT2AHDAC3HDAC4HDAC1HDAC7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 819 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240400784-A1 Method for Screening Solvent for Extracting Polyvinyl Chloride, Method for Recycling Waste, Recycled Polyvinyl Chloride, and Composition LG CHEM, LTD. (KR) 2024-12-05 US claimed
US-20240392094-A1 Method for Screening Solvent for Polyvinyl Chloride Extraction, Recycling Method for Waste Material, and Recycled Polyvinyl Chloride and Composition LG CHEM, LTD. (KR) 2024-11-28 US claimed
CN-117534631-B Phenylthiazole amine PI4KIII beta inhibitor, preparation method, pharmaceutical composition and application thereof 南京市鸿舜医药科技有限公司 2024-04-05 CN claimed
CN-117534631-A Phenylthiazole amine PI4KIII beta inhibitor, preparation method, pharmaceutical composition and application thereof 南京市鸿舜医药科技有限公司 2024-02-09 CN claimed
CN-113185386-B Rapid synthesis method of biomass-based olefin 贵州大学 2023-05-30 CN claimed
CN-115925527-A Method for preparing alpha-diaryl methyl substituted ketone compound 湖南理工学院 2023-04-07 CN claimed
CN-111116375-B Method for preparing primary amine by catalyzing aldehyde ketone compound through reductive amination 中国科学院广州能源研究所 2023-04-07 CN claimed
WO-2023033605-A1 METHOD FOR SCREENING SOLVENT FOR EXTRACTING POLYVINYL CHLORIDE, METHOD FOR RECYCLING WASTE, RECYCLED POLYVINYL CHLORIDE, AND COMPOSITION 주식회사 엘지화학 2023-03-09 WO claimed
WO-2023033601-A1 METHOD FOR SCREENING SOLVENT FOR POLYVINYL CHLORIDE EXTRACTION, RECYCLING METHOD FOR WASTE MATERIAL, AND RECYCLED POLYVINYL CHLORIDE AND COMPOSITION 주식회사 엘지화학 2023-03-09 WO claimed
CN-114858944-B Method for detecting p-methoxypropiophenone related substances 石家庄四药有限公司 2023-02-03 CN claimed
CN-109180705-B Fluorescent compound and preparation method and application thereof 五邑大学 2021-06-08 CN claimed
CN-112522224-A Alcohol dehydrogenase mutant with improved activity and stereoselectivity, recombinant vector, genetic engineering bacteria and application thereof 华东理工大学 2021-03-19 CN claimed
CN-111170900-A Preparation method of tamsulosin impurity with high optical purity 珠海润都制药股份有限公司 2020-05-19 CN claimed
CN-111116375-A Method for preparing primary amine by catalyzing aldehyde ketone compound through reductive amination 中国科学院广州能源研究所 2020-05-08 CN claimed
CN-109400518-A Polysubstituted 6- aryl benzo [a] carbazole and derivative and its synthetic method 湘潭大学 2019-03-01 CN claimed
CN-109180515-A A kind of synthetic method of N- [2- hydroxyl -2- (4- methoxyphenyl) ethyl] cinnamamide 苏利制药科技江阴有限公司 2019-01-11 CN claimed
CN-107935829-A The efficient green synthetic method of p-methoxyphenyl ethyl ketone 苏州盖德精细材料有限公司 2018-04-20 CN claimed
CN-102665652-B Hydrogel particles KAO CORP 2014-07-16 CN claimed
EP-1738646-B1 Forming germicidal aromatic dialdehydes with acetals ETHICON INC (US) 2013-03-20 EP claimed
US-20110239736-A1 Whole Mouth Malador Control By A Combination Of Antibacterial And Deodorizing Agents THE PROCTER & GAMBLE COMPANY 2011-10-06 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110239736-A1 Whole Mouth Malador Control By A Combination Of Antibacterial And Deodorizing Agents OR10J3, HDAC10, RPP30 KMT2A 3605/4885HDAC3 415/4885HDAC4 976/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.