Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC5 | P28715 | 1/20 | 0.64 |
| ▸ | FEN1 | P39748 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
| ▸ | MMP1 | P03956 | 1/20 | 0.58 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.53 |
| ▸ | LTA4H | P09960 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | CRHBP | P24387 | 1/20 | 0.50 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11052292 | 0.92 | MAPT (0.58) | ERCC5FEN1SMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL7860509 | 0.91 | SMN1; SMN2 (0.79) | ERCC5FEN1SMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL6032575 | 0.85 | L3MBTL1 (0.66) | ERCC5FEN1SMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL5279835 | 0.85 | PKM (0.68) | SMN1; SMN2MAPTL3MBTL1PARP10RAB9A | |
| SCHEMBL6061938 | 0.85 | PARP10 (0.58) | SMN1; SMN2MAPTPARP10RAB9ANPC1 | |
| SCHEMBL11955348 | 0.85 | KMT2A (0.64) | MAPTMMP1PARP10RAB9AALDH1A1 | |
| SCHEMBL27504557 | 0.84 | SMN1; SMN2 (0.53) | ERCC5FEN1SMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL9814634 | 0.84 | MMP1 (0.77) | ERCC5FEN1SMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL10455392 | 0.84 | ERCC5 (0.67) | ERCC5FEN1SMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL6142809 | 0.83 | MMP1 (0.59) | SMN1; SMN2MAPTL3MBTL1MMP1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102341494-B | Transaminase polypeptides | CODEXIS, INC. (US) | 2014-10-15 | — | — | CN | claimed |
| CN-102341494-A | TRANSAMINASE POLYPEPTIDES | CODEXIS INC | 2012-02-01 | — | — | CN | claimed |
| EP-0003002-B1 | USE OF AROMATIC-ALIPHATIC KETONES AS PHOTOINITIATORS, PHOTOPOLYMERISABLE SYSTEMS CONTAINING SUCH KETONES AND AROMATIC-ALIPHATIC KETONES | CIBA-GEIGY AG (CH) | 1984-06-13 | — | — | EP | claimed |
| WO-2020141439-A1 | HETEROCYCLIC COMPOUNDS AS MUTANT IDH INHIBITORS | INTEGRAL BIOSCIENCES PRIVATE LIMITED (IN) | 2020-07-09 | — | — | WO | disclosed |
| US-20200206233-A1 | HETEROCYCLIC COMPOUNDS AS MUTANT IDH INHIBITORS | INTEGRAL BIOSCIENCES PRIVATE LIMITED (IN) | 2020-07-02 | — | — | US | disclosed |
| US-20200206233-A1 | HETEROCYCLIC COMPOUNDS AS MUTANT IDH INHIBITORS | INTEGRAL BIOSCIENCES PRIVATE LIMITED (IN) | 2020-07-02 | — | — | US | disclosed |
| US-20190040269-A1 | POWDER COMPOSITION OF POLYARYLENE ETHER KETONE KETONES ALLOWING AN EXCELLENT CASTABILITY/COALESCENCE BALANCE SUITABLE FOR LASER SINTERING | ARKEMA FRANCE (FR) | 2019-02-07 | — | — | US | disclosed |
| CN-108602818-A | Pyrazole fused ring analog derivative, preparation method and its application in treating cancer, inflammation and immunity disease | 北京诺诚健华医药科技有限公司 | 2018-09-28 | — | — | CN | disclosed |
| CN-107226805-A | Aromatic amides analog derivative, its preparation method and its in application pharmaceutically | 北京天诚医药科技有限公司 | 2017-10-03 | — | — | CN | disclosed |
| US-20170253696-A1 | METHOD FOR MAKING POLYARYLALIPHATICETHERKETONE POLYMERS AND COPOLYMERS THEREOF | OXFORD PERFORMANCE MATERIALS, INC | 2017-09-07 | — | — | US | disclosed |
| CN-106588806-A | Bromophenol-oxazole compound and its use in drug for treatment on diabetes mellitus type 2 | 中国科学院海洋研究所 | 2017-04-26 | — | — | CN | disclosed |
| EP-1638909-A2 | PROCESS FOR PREPARING ALKOXY- AND ARYLOXY-PHENOLS | ENDURA S.p.A. (IT) | 2006-03-29 | — | — | EP | disclosed |
| WO-2004092106-A2 | PROCESS FOR PREPARING ALKOXY- AND ARYLOXY-PHENOLS | ENDURA S.P.A. (IT) | 2004-10-28 | — | — | WO | disclosed |
| US-5266585-A | Controlling phytopathogenic microorganisms, fungicides, antimycotics, anticonvulsives and/or anxiolytic agents | CIBA-GEIGY CORPORATION (US) | 1993-11-30 | — | — | US | disclosed |
| EP-0324472-B1 | KETENEDITHIOACETAL DERIVATIVES AND PROCESSES FOR PRODUCING THE SAME AS WELL AS A COMPOSITION CONTAINING THE SAME | NIHON NOHYAKU CO., LTD. (JP) | 1992-09-02 | — | — | EP | disclosed |
| US-5098928-A | Antilipemic agents and treatment of arteriosclerosis | NIHON NOHYAKU CO., LTD. (JP) | 1992-03-24 | — | — | US | disclosed |
| EP-0324472-A2 | Ketenedithioacetal derivatives and processes for producing the same as well as a composition containing the same | NIHON NOHYAKU CO., LTD. (JP) | 1989-07-19 | — | — | EP | disclosed |
| EP-0112284-A2 | Arylphenyl ether derivatives | CIBA-GEIGY AG (CH) | 1984-06-27 | — | — | EP | disclosed |
| EP-0009683-A1 | Basic phenyl ethers, pharmaceutical compositions containing them and the preparation of these ethers and compositions | MERCK PATENT GmbH (DE) | 1980-04-16 | — | — | EP | disclosed |
| US-3932530-A | ANTIINFLAMMATORY AGENTS | SANDOZ, INC. (US) | 1976-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200206233-A1 | HETEROCYCLIC COMPOUNDS AS MUTANT IDH INHIBITORS | IDH1, IDH2, IDH3A | ERCC5 1551/4885FEN1 2562/4885SMN1; SMN2 1763/4885 |
| US-20170253696-A1 | METHOD FOR MAKING POLYARYLALIPHATICETHERKETONE POLYMERS AND COPOLYMERS THEREOF | COASY, FRK, PBK | ERCC5 2918/4885FEN1 3558/4885SMN1; SMN2 4677/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.