Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.74 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.58 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.58 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.58 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.58 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.58 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.58 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.58 |
| ▸ | GSK3B | P49841 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.56 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL459470 | 0.91 | KMT2A (0.70) | KMT2AHDAC3HDAC4HDAC1HDAC7 | |
| Butane SCHEMBL10982980 | 0.87 | KMT2A (0.66) | KMT2AHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL5630152 | 0.87 | KMT2A (0.60) | KMT2AHDAC1HDAC6RAB9ANPC1 | |
| SCHEMBL11955348 | 0.85 | KMT2A (0.64) | KMT2AHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL7859470 | 0.85 | KMT2A (0.64) | KMT2AHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL2099619 | 0.85 | RAB9A (0.78) | KMT2ARAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL9607150 | 0.84 | MTNR1A (0.59) | KMT2AHDAC1RAB9ANPC1LMNA | |
| SCHEMBL28232519 | 0.83 | RAB9A (0.63) | KMT2ARAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL2689787 | 0.83 | KMT2A (0.61) | KMT2ARAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL5616579 | 0.81 | KMT2A (0.73) | KMT2AGSK3BRAB9ANPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012069856-A1 | ANTIMALARIAL COMPOUNDS | LIVERPOOL SCHOOL OF TROPICAL MEDICINE (GB) | 2012-05-31 | — | — | WO | disclosed |