Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 7/20 | 0.34 |
| ▸ | DRD3 | P35462 | 2/20 | 0.33 |
| ▸ | ACACB | O00763 | 2/20 | 0.33 |
| ▸ | ACACA | Q13085 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 2/20 | 0.32 |
| ▸ | CCR1 | P32246 | 2/20 | 0.31 |
| ▸ | MAOB | P27338 | 2/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12507711 | 0.90 | MAOA (0.33) | DRD2DRD3ACACBACACAEPHX2 | |
| SCHEMBL10280029 | 0.86 | CCR1 (0.39) | EPHX2KMT2AL3MBTL1KDM1ACCR1 | |
| SCHEMBL12101100 | 0.78 | EPHX2 (0.36) | DRD2EPHX2KDM1ACCR1MAOB | |
| SCHEMBL4094101 | 0.77 | F10 (0.50) | — | |
| SCHEMBL3340284 | 0.77 | F10 (0.50) | — | |
| SCHEMBL10476622 | 0.77 | F10 (0.50) | — | |
| SCHEMBL4275693 | 0.77 | F10 (0.50) | — | |
| SCHEMBL3340287 | 0.77 | F10 (0.50) | — | |
| SCHEMBL15045022 | 0.75 | SMN1; SMN2 (0.38) | ACACBACACA | |
| SCHEMBL12507710 | 0.71 | STS (0.41) | L3MBTL1MAPK8ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1405852-B1 | DIAMINE DERIVATIVES | DAIICHI SANKYO CO LTD (JP) | 2012-08-01 | — | — | EP | disclosed |