Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.34 |
| ▸ | RELA | Q04206 | 2/20 | 0.34 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 2/20 | 0.32 |
| ▸ | CCR1 | P32246 | 1/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10280029 | 0.85 | CCR1 (0.39) | EPHX2NFKB1NFKB2RELAKDM1A | |
| SCHEMBL11959792 | 0.78 | DRD2 (0.34) | EPHX2MAPK8KDM1ACCR1MAOB | |
| SCHEMBL12507711 | 0.76 | MAOA (0.33) | EPHX2KDM1ACCR1MAOBDRD2 | |
| SCHEMBL4273282 | 0.74 | EHMT2 (0.49) | — | |
| SCHEMBL4274704 | 0.74 | EHMT2 (0.49) | — | |
| SCHEMBL4273278 | 0.74 | EHMT2 (0.49) | — | |
| SCHEMBL12507710 | 0.72 | STS (0.41) | MAPK8 | |
| SCHEMBL28454474 | 0.71 | EPHX2 (0.48) | EPHX2GAANFKB1NFKB2RELA | |
| SCHEMBL29500783 | 0.71 | EPHX2 (0.48) | EPHX2GAANFKB1NFKB2RELA | |
| SCHEMBL12101124 | 0.71 | TRPA1 (0.38) | EPHX2GAASCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1577301-B1 | Antithrombotic diaminocyclohexane derivatives | DAIICHI SANKYO CO LTD (JP) | 2012-09-12 | — | — | EP | disclosed |