Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 5/20 | 0.41 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 2/20 | 0.39 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.38 |
| ▸ | CNR1 | P21554 | 2/20 | 0.38 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12056140 | 0.76 | STS (0.39) | STSNPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL3336715 | 0.75 | F10 (0.63) | F10 | |
| SCHEMBL2940528 | 0.75 | F10 (0.63) | F10 | |
| SCHEMBL3336718 | 0.75 | F10 (0.63) | F10 | |
| SCHEMBL12101100 | 0.72 | EPHX2 (0.36) | MAPK8 | |
| SCHEMBL27349799 | 0.71 | USP30 (0.48) | STSUSP30NPC1RAB9AMAPT | |
| SCHEMBL11959792 | 0.71 | DRD2 (0.34) | ALDH1A1L3MBTL1MAPK8 | |
| SCHEMBL18345764 | 0.69 | CNR1 (0.44) | STSUSP30NPC1RAB9AMAPT | |
| SCHEMBL16512911 | 0.69 | USP30 (0.50) | STSUSP30NPC1RAB9AMAPT | |
| SCHEMBL15197029 | 0.69 | STS (0.50) | STS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2343290-A1 | Diamine derivatives as factor X inhibitors | Daiichi Sankyo Company, Limited (JP) | 2011-07-13 | — | — | EP | disclosed |