SCHEMBL1196003

SCHEMBL1196003

CCCC1CCCC(C)C(C(=O)OC(C)C)C1C(=O)OC(C)C

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA4 P22748 1/20 0.35
ALDH1A1 P00352 1/20 0.32
MAPT P10636 1/20 0.32
HMGCR P04035 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1196092 0.91 MAPT (0.35) CA1CA2CA4ALDH1A1MAPT
SCHEMBL1245696 0.84 TSHR (0.36) ALDH1A1MAPT
SCHEMBL1195433 0.83 LMNA (0.32) CA1CA2CA4ALDH1A1MAPT
SCHEMBL1196483 0.83 RAB9A (0.33) CA1CA2CA4ALDH1A1HMGCR
SCHEMBL1195966 0.82 PPM1B (0.40) CA1CA2CA4ALDH1A1MAPT
SCHEMBL1196337 0.81 PPM1B (0.43) CA1CA2CA4ALDH1A1HMGCR
SCHEMBL1196803 0.78 MAPT (0.36) ALDH1A1MAPT
SCHEMBL1196000 0.78 ALDH1A1 (0.36) CA1CA2CA4ALDH1A1
SCHEMBL1196590 0.77 ALDH1A1 (0.40) ALDH1A1MAPT
SCHEMBL1196578 0.76 PPARG (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2221320-B1 SOLID TITANIUM CATALYST INGREDIENT, CATALYST FOR OLEFIN POLYMERIZATION, AND METHOD OF POLYMERIZING OLEFIN MITSUI CHEMICALS INC (JP) 2017-06-21 EP disclosed
EP-1845113-B1 SOLID TITANIUM CATALYST COMPONENT, CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER MITSUI CHEMICALS INC (JP) 2015-04-01 EP disclosed
US-8742040-B2 Solid titanium catalyst component, olefin polymerization catalyst, and olefin polymerization process MITSUI CHEMICALS, INC. (JP) 2014-06-03 US disclosed
US-7888438-B2 A solid titanium catalyst component comprising titanium, magnesium, halogen, and a C5-C10 carbocyclic diester, and an organometallic component; moldable polyolefins having broad molecular weight distribution MITSUI CHEMICALS, INC. (JP) 2011-02-15 US disclosed
US-20100305285-A1 SOLID TITANIUM CATALYST COMPONENT, OLEFIN POLYMERIZATION CATALYST, AND OLEFIN POLYMERIZATION PROCESS MITSUI CHEMICALS, INC. 2010-12-02 US disclosed
EP-2221320-A1 SOLID TITANIUM CATALYST INGREDIENT, CATALYST FOR OLEFIN POLYMERIZATION, AND METHOD OF POLYMERIZING OLEFIN Mitsui Chemicals, Inc. (JP) 2010-08-25 EP disclosed
US-7649062-B2 Solid titanium catalyst component, catalyst for polymerization of olefin and process for producing olefin polymer MITSUI CHEMICALS, INC. (JP) 2010-01-19 US disclosed
US-20090069515-A1 Solid Titanium Catalyst Component, Catalyst for Polymerization of Olefin and Process for Producing Olefin Polymer MITSUI CHEMICALS,INC. (JP) 2009-03-12 US disclosed
US-20080097050-A1 Solid titanium catalyst component, catalyst for polymerization of olefin and process for producing olefin polymer MITSUI CHEMICALS, INC. (JP) 2008-04-24 US disclosed
EP-1845113-A1 SOLID TITANIUM CATALYST COMPONENT, CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER Mitsui Chemicals, Inc. (JP) 2007-10-17 EP disclosed