Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA7 | P43166 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11955135 | 0.86 | TSHR (0.44) | ALDH1A1HSD17B10GAAMAPK1TSHR | |
| SCHEMBL1966248 | 0.84 | ALDH1A1 (0.54) | ALDH1A1HSD17B10GAAMAPK1TSHR | |
| SCHEMBL2596428 | 0.83 | ALDH1A1 (0.53) | ALDH1A1HSD17B10GAAMAPK1TSHR | |
| SCHEMBL20362396 | 0.81 | HTR4 (0.47) | ALDH1A1HSD17B10GAATSHRKMT2A | |
| SCHEMBL13108747 | 0.80 | TSHR (0.39) | ALDH1A1HSD17B10MAPK1TSHRMEN1 | |
| SCHEMBL17930512 | 0.78 | ALDH1A1 (0.51) | ALDH1A1HSD17B10GAAMAPK1TSHR | |
| SCHEMBL11962194 | 0.78 | ALDH1A1 (0.40) | ALDH1A1HSD17B10GAAMAPK1TSHR | |
| SCHEMBL11956092 | 0.77 | ALDH1A1 (0.38) | ALDH1A1HSD17B10TSHRKMT2AJMJD6 | |
| SCHEMBL23590720 | 0.77 | TSHR (0.41) | ALDH1A1HSD17B10GAAMAPK1TSHR | |
| SCHEMBL11955480 | 0.77 | TSHR (0.41) | ALDH1A1HSD17B10GAAMAPK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120196897-A1 | NEW COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-08-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120196897-A1 | NEW COMPOUNDS | MTX1, LTB4R, RDX | ALDH1A1 1761/4885HSD17B10 4020/4885GAA 1712/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.