SCHEMBL11963207

SCHEMBL11963207

C[C@@H]1CN(C(=O)OC(C)(C)C)CCN1c1cc(Br)ccn1

nearest known ligand 0.50

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 13/20 0.50
SMARCA2 P51531 1/20 0.48
SMARCA4 P51532 1/20 0.48
PBRM1 Q86U86 1/20 0.48
ABCB1 P08183 1/20 0.45
USP30 Q70CQ3 1/20 0.44
SETD7 Q8WTS6 1/20 0.42
GRM1 Q13255 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29182666 1.00 GPR119 (0.50) GPR119SMARCA2SMARCA4PBRM1ABCB1
SCHEMBL11963206 1.00 GPR119 (0.50) GPR119SMARCA2SMARCA4PBRM1ABCB1
SCHEMBL38663929 0.87 GPR119 (0.42) GPR119SMARCA2SMARCA4PBRM1USP30
SCHEMBL38664491 0.87 GPR119 (0.42) GPR119SMARCA2SMARCA4PBRM1USP30
SCHEMBL38666126 0.87 GPR119 (0.50) GPR119SMARCA2SMARCA4PBRM1ABCB1
SCHEMBL17871504 0.87 MMP2 (0.51) GPR119SMARCA2SMARCA4PBRM1ABCB1
SCHEMBL17871501 0.87 MMP2 (0.51) GPR119SMARCA2SMARCA4PBRM1ABCB1
SCHEMBL38666600 0.86 GPR119 (0.42) GPR119SMARCA2SMARCA4PBRM1USP30
SCHEMBL38665446 0.86 GPR119 (0.42) GPR119SMARCA2SMARCA4PBRM1USP30
SCHEMBL38663913 0.86 GPR119 (0.42) GPR119SMARCA2SMARCA4PBRM1USP30

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026106389-A1 NMT INHIBITOR AND USE THEREOF 주식회사 이노보테라퓨틱스 2026-05-21 WO disclosed
EP-2489663-A1 Compounds as syk kinase inhibitors Almirall, S.A. (ES) 2012-08-22 EP disclosed