SCHEMBL119730

SCHEMBL119730

Nc1ncc(C(F)(F)F)cc1Cl

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.59
SMN1; SMN2 Q16637 3/20 0.59
POLB P06746 2/20 0.59
KDM4E B2RXH2 2/20 0.59
PLAU P00749 1/20 0.54
CYP1A2 P05177 1/20 0.50
CYP3A4 P08684 1/20 0.50
CYP2C19 P33261 1/20 0.50
GAA P10253 2/20 0.49
HTT P42858 4/20 0.47
L3MBTL1 Q9Y468 2/20 0.46
TDP1 Q9NUW8 1/20 0.46
MAPT P10636 3/20 0.45
LMNA P02545 1/20 0.45
GLA P06280 1/20 0.45
HPGD P15428 1/20 0.45
NPC1 O15118 2/20 0.44
RAB9A P51151 2/20 0.44
NPSR1 Q6W5P4 2/20 0.44
MEN1 O00255 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methane SCHEMBL3560123 0.98 ALDH1A1 (0.57) ALDH1A1SMN1; SMN2POLBKDM4EPLAU
SCHEMBL18094306 0.84 ALDH1A1 (0.47) ALDH1A1SMN1; SMN2POLBKDM4EPLAU
SCHEMBL30256557 0.84 ALDH1A1 (0.44) ALDH1A1SMN1; SMN2POLBKDM4EPLAU
SCHEMBL24068078 0.84 ALDH1A1 (0.44) ALDH1A1SMN1; SMN2POLBKDM4EPLAU
SCHEMBL20350719 0.81 TSHR (0.41) ALDH1A1SMN1; SMN2POLBKDM4EPLAU
SCHEMBL15181426 0.79 ALDH1A1 (0.39) ALDH1A1SMN1; SMN2POLBKDM4EPLAU
SCHEMBL120994 0.78 ALDH1A1 (0.56) ALDH1A1SMN1; SMN2POLBKDM4EPLAU
SCHEMBL29414916 0.78 ALDH1A1 (0.56) ALDH1A1SMN1; SMN2POLBKDM4EPLAU
SCHEMBL30762204 0.78 ALDH1A1 (0.44) ALDH1A1SMN1; SMN2POLBKDM4EPLAU
SCHEMBL1716472 0.78 ALDH1A1 (0.44) ALDH1A1SMN1; SMN2POLBKDM4EPLAU

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 634 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119264043-A High-quality fluazinam high-efficiency synthesis process 吴忠领航生物药业科技有限公司 2025-01-07 CN claimed
WO-2024259993-A1 BRAKING ENERGY RECOVERY CONTROL METHOD AND APPARATUS, CONTROL SYSTEM, VEHICLE, AND MEDIUM 重庆长安汽车股份有限公司 2024-12-26 WO claimed
CN-118317063-A Projector control system and control method 孙晓晨 2024-07-09 CN claimed
CN-117777129-A Synthesis method of trifluramide 利民化学有限责任公司 2024-03-29 CN claimed
CN-115181060-B Clean production process for producing 2-amino-3-chloro-5-trifluoromethyl pyridine 江苏禾裕泰化学有限公司 2024-03-19 CN claimed
CN-113651718-B 1, 1-dicyanooxime ether compound and application thereof 沈阳化工大学 2023-10-20 CN claimed
CN-113527194-B Preparation method of 2-amino-3-chloro-5-trifluoromethyl pyridine 武威广达科技有限公司 2023-10-03 CN claimed
CN-116552253-A Braking energy recovery control method, device, control system, vehicle and medium 重庆长安汽车股份有限公司 2023-08-08 CN claimed
CN-116308732-A Integrated algorithm-based overdue prediction method for public accumulation personal loan 赵作铭 2023-06-23 CN claimed
CN-115850865-A Photovoltaic corrosion-resistant anti-aging polypropylene plate and preparation method thereof 江阴瑞林精密机械制造有限公司 2023-03-28 CN claimed
CN-101343366-A Nano-laminal compound with regular array of pyridine and its derivant, and preparation thereof UNIV SHANGHAI (CN) 2009-01-14 CN claimed
EP-1727799-B1 NOVEL ALKYL-CONTAINING 5-ACYLINDOLINONES, THEIR PREPARATION AND THEIR USE AS PHARMACEUTICAL PRODUCTS BOEHRINGER INGELHEIM INT (DE) 2009-01-07 EP claimed
US-20050209302-A1 Alkyl-containing 5-acylindolinones, the preparation thereof and their use as medicaments BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2005-09-22 US claimed
US-5897940-A Ink jet transparencies XEROX CORPORATION (US) 1999-04-27 US claimed
EP-0596491-B1 Method for halogenating an aromatic compound ISHIHARA SANGYO KAISHA (JP) 1996-07-10 EP claimed
US-5491239-A Method for halogenating an aromatic compound ISHIHARA SANGYO KAISHA LTD. (JP) 1996-02-13 US claimed
EP-0596491-A1 Method for halogenating an aromatic compound ISHIHARA SANGYO KAISHA, LTD. (JP) 1994-05-11 EP claimed
EP-0031218-B1 A 2-AMINO-TRIFLUOROMETHYL-HALOGENOPYRIDINE COMPOUND AND A PROCESS FOR PRODUCING THE SAME ISHIHARA SANGYO KAISHA LTD. (JP) 1983-05-11 EP claimed
US-4349681-A 2-Amino-3-chloro-5-trifluoromethylpyridine ISHIHARA SANGYO KAISHA, LTD. (JP) 1982-09-14 US claimed
EP-0031218-A1 A 2-amino-trifluoromethyl-halogenopyridine compound and a process for producing the same ISHIHARA SANGYO KAISHA LTD. (JP) 1981-07-01 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050209302-A1 Alkyl-containing 5-acylindolinones, the preparation thereof and their use as medicaments GSK3A, GSK3B, PYGL ALDH1A1 2722/4885SMN1; SMN2 3715/4885POLB 3759/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.