Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4264379 | 0.70 | — | — | |
| SCHEMBL15202449 | 0.65 | NPSR1 (0.30) | NPSR1 | |
| SCHEMBL9787463 | 0.61 | LTB4R (0.49) | KDM4ENPSR1 | |
| SCHEMBL3433172 | 0.61 | — | — | |
| SCHEMBL10362767 | 0.61 | — | — | |
| SCHEMBL11210558 | 0.61 | NPSR1 (0.44) | NPSR1 | |
| SCHEMBL461574 | 0.61 | — | — | |
| SCHEMBL4078236 | 0.60 | — | — | |
| Hydrochloric Acid SCHEMBL11211543 | 0.60 | NPSR1 (0.43) | NPSR1 | |
| SCHEMBL5491905 | 0.59 | NPSR1 (0.39) | NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103491938-B | Comprise the oxidative dye compositions of 1 hexyl/heptyl 4,5 diamino-pyrazole and m-aminophenol and its derivant | 宝洁公司 | 2017-03-08 | — | — | CN | disclosed |
| CN-103379939-B | Comprise the oxidative dye compositions of 1 hexyl/heptyl 4,5 diamino-pyrazole and pyridine and its derivatives | 宝洁公司 | 2016-12-07 | — | — | CN | disclosed |
| CN-103379894-B | Comprise 1-hexyl/heptyl-4,5-diamino-pyrazole and 1,3-phenylenediamine and the oxidative dye compositions of derivant thereof | 宝洁公司 | 2016-11-02 | — | — | CN | disclosed |
| CN-103442682-B | Oxidative dyeing composition comprising 1-hexyl/heptyl-4, 5-diaminopyrazole and naphthalen-1-ol and derivatives thereof | 宝洁公司 | 2016-08-31 | — | — | CN | disclosed |
| CN-103491937-B | Oxidative dyeing composition comprising 1-hexyl/heptyl-4, 5-diaminopyrazole and 2-aminophenol and derivatives thereof | 宝洁公司 | 2016-08-31 | — | — | CN | disclosed |
| CN-103533919-B | Oxidative dyeing composition comprising 1-hexyl/heptyl-4, 5-diaminopyrazole and 1, 3-benzenediol and derivatives thereof | 宝洁公司 | 2016-06-15 | — | — | CN | disclosed |
| CN-103458863-B | Comprise 1-hexyl/heptyl-4, the oxidative coloration composition of 5-diamino-pyrazole and benzo [1,3] dioxole-5-base amine and derivative thereof | THE PROCTER & GAMBLE CO. (US) | 2016-05-04 | — | — | CN | disclosed |
| CN-103533919-A | Oxidative dyeing composition comprising 1-hexyl/heptyl-4, 5-diaminopyrazole and 1, 3-benzenediol and derivatives thereof | PROCTER & GAMBLE | 2014-01-22 | — | — | CN | disclosed |
| CN-103491937-A | Oxidative dyeing composition comprising 1-hexyl/heptyl-4, 5-diaminopyrazole and 2-aminophenol and derivatives thereof | PROCTER & GAMBLE | 2014-01-01 | — | — | CN | disclosed |
| CN-103491938-A | Oxidative dyeing compositions comprising an 1-hexyl/heptyl-4,5-diaminopyrazole and a m-aminophenol and derivatives thereof | PROCTER & GAMBLE | 2014-01-01 | — | — | CN | disclosed |
| CN-103458863-A | Oxidative dyeing composition comprising 1-hexyl/heptyl-4,5-diaminopyrazole and benzo[1,3]dioxol-5-ylamine and derivatives thereof | PROCTER & GAMBLE | 2013-12-18 | — | — | CN | disclosed |
| CN-103442682-A | Oxidative dyeing composition comprising 1-hexyl/heptyl-4, 5-diaminopyrazole and naphthalen-1-ol and derivatives thereof | PROCTER & GAMBLE | 2013-12-11 | — | — | CN | disclosed |
| CN-103379939-A | Oxidative dyeing compositions comprising an 1-hexyl/heptyl-4,5-diaminopyrazole and a pyridine and derivatives thereof | PROCTER & GAMBLE | 2013-10-30 | — | — | CN | disclosed |
| CN-103379894-A | Oxidative dyeing compositions comprising an 1-hexyl/heptyl-4,5-diaminopyrazole and a benzene-1,3-diamine and derivatives thereof | PROCTER & GAMBLE | 2013-10-30 | — | — | CN | disclosed |
| WO-2013105992-A1 | OXIDATIVE DYEING COMPOSITIONS COMPRISING AN 1-HEXYL/HEPTYL-4,5-DIAMINOPYRAZOLE AND A PYRIDINE AND DERIVATIVES THEREOF | THE PROCTER & GAMBLE COMPANY (US) | 2013-07-18 | — | — | WO | disclosed |
| US-8460397-B2 | Oxidative dyeing compositions comprising an 1-hexyl/heptyl-4,5-diaminopyrazole and a pyridine and derivatives thereof | THE PROCTER & GAMBLE COMPANY (US) | 2013-06-11 | — | — | US | disclosed |
| US-20120210526-A1 | Oxidative Dyeing Compositions Comprising an 1-Hexyl/Heptyl-4,5-diaminopyrazole and a Pyridine and Derivatives Thereof | WELLA OPERATIONS US, LLC | 2012-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120210526-A1 | Oxidative Dyeing Compositions Comprising an 1-Hexyl/Heptyl-4,5-diaminopyrazole and a Pyridine and Derivatives Thereof | KRT18, NOX4, AOC1 | KDM4E 1706/4885NPSR1 3981/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.