Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | ABL1 | P00519 | 1/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | IDE | P14735 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.59 |
| ▸ | HLCS | P50747 | 6/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19054924 | 1.00 | TDP1 (0.59) | TDP1LMNAMEN1KMT2AL3MBTL1 | |
| SCHEMBL11983712 | 0.88 | TDP1 (0.51) | TDP1LMNAMEN1KMT2AL3MBTL1 | |
| SCHEMBL20342144 | 0.87 | TDP1 (0.45) | TDP1LMNAMEN1KMT2AL3MBTL1 | |
| SCHEMBL21390226 | 0.83 | TDP1 (0.44) | TDP1LMNAMEN1KMT2AL3MBTL1 | |
| SCHEMBL22473613 | 0.80 | FAAH (0.42) | TDP1LMNAMEN1KMT2AL3MBTL1 | |
| SCHEMBL22037753 | 0.80 | HLCS (0.55) | TDP1LMNAMEN1KMT2AL3MBTL1 | |
| SCHEMBL22364111 | 0.79 | TDP1 (0.47) | TDP1LMNAMEN1KMT2AL3MBTL1 | |
| SCHEMBL18881123 | 0.78 | TDP1 (0.49) | TDP1LMNAMEN1KMT2AL3MBTL1 | |
| SCHEMBL2608511 | 0.77 | HLCS (0.39) | TDP1LMNAMEN1KMT2AL3MBTL1 | |
| SCHEMBL14586595 | 0.77 | TDP1 (0.61) | TDP1LMNAMEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220396584-A1 | BIOTIN-CONTAINING MONOMERS AND ARTICLES FORMED THEREFROM | SOLVENTUM INTELLECTUAL PROPERTIES COMPANY | 2022-12-15 | — | — | US | disclosed |
| US-20120207684-A1 | COMPOSITION AND METHODS FOR IMAGING CELLS | CASE WESTERN RESERVE UNIVERSITY | 2012-08-16 | — | — | US | disclosed |
| US-20120207684-A1 | COMPOSITION AND METHODS FOR IMAGING CELLS | CASE WESTERN RESERVE UNIVERSITY | 2012-08-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120207684-A1 | COMPOSITION AND METHODS FOR IMAGING CELLS | MCL1, TP53, HNRNPAB | TDP1 3017/4885LMNA 808/4885MEN1 413/4885 |
| US-20220396584-A1 | BIOTIN-CONTAINING MONOMERS AND ARTICLES FORMED THEREFROM | BTD, BPGM, STAMBP | TDP1 3418/4885LMNA 2540/4885MEN1 2641/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.