SCHEMBL11977475

SCHEMBL11977475

CC(C)(C)c1ccc(N)o1

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.32
MITF O75030 1/20 0.32
KDM4E B2RXH2 1/20 0.31
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL47577 0.80 MITF (0.36) L3MBTL1MITF
SCHEMBL12743957 0.72
SCHEMBL420157 0.70 TDP1 (0.53) L3MBTL1MITF
SCHEMBL2889732 0.69
SCHEMBL6695496 0.69 CYP2D6 (0.41) MITF
SCHEMBL799935 0.68 MEN1 (0.32) MITFNPC1RAB9A
SCHEMBL22480890 0.68 MITF (0.32) MITF
SCHEMBL9769187 0.68 MITF (0.32) MITF
SCHEMBL21720511 0.68 MITF (0.32) MITF
SCHEMBL21720376 0.68 MITF (0.32) MITF

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2495016-B1 Bicyclic Heteroaryl Compounds ARIAD PHARMA INC (US) 2019-10-16 EP disclosed
US-10283719-B2 Organic thin-film transistor and method for manufacturing the same, material for organic thin-film transistor, composition for organic thin-film transistor, compound, and organic semiconductor film FUJIFILM CORPORATION (JP) 2019-05-07 US disclosed
US-20180159048-A1 ORGANIC THIN-FILM TRANSISTOR AND METHOD FOR MANUFACTURING THE SAME, MATERIAL FOR ORGANIC THIN-FILM TRANSISTOR, COMPOSITION FOR ORGANIC THIN-FILM TRANSISTOR, COMPOUND, AND ORGANIC SEMICONDUCTOR FILM FUJIFILM CORPORATION (JP) 2018-06-07 US disclosed
US-8889732-B2 Fused heterocyclic compounds and thrombopoietin receptor activators NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2014-11-18 US disclosed
US-20120209005-A1 FUSED HETEROCYCLIC COMPOUNDS AND THROMBOPOIETIN RECEPTOR ACTIVATORS NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2012-08-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120209005-A1 FUSED HETEROCYCLIC COMPOUNDS AND THROMBOPOIETIN RECEPTOR ACTIVATORS MPL, TEK, THPO L3MBTL1 477/4885MITF 1200/4885KDM4E 4664/4885
US-20180159048-A1 ORGANIC THIN-FILM TRANSISTOR AND METHOD FOR MANUFACTURING THE SAME, MATERIAL FOR ORGANIC THIN-FILM TRANSISTOR, COMPOSITION FOR ORGANIC THIN-FILM TRANSISTOR, COMPOUND, AND ORGANIC SEMICONDUCTOR FILM SLCO2A1, SLCO4C1, SLCO2B1 L3MBTL1 2226/4885MITF 492/4885KDM4E 2778/4885
US-10283719-B2 Organic thin-film transistor and method for manufacturing the same, material for organic thin-film transistor, composition for organic thin-film transistor, compound, and organic semiconductor film SLCO2A1, SLCO4C1, SLCO2B1 L3MBTL1 2226/4885MITF 492/4885KDM4E 2778/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.