SCHEMBL22480890

SCHEMBL22480890

CC(C)(C)c1ccc(S)o1

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
MITF O75030 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL47577 0.80 MITF (0.36) MITF
SCHEMBL10680944 0.69 ALDH1A1 (0.32)
SCHEMBL11977475 0.68 L3MBTL1 (0.32) MITF
SCHEMBL21720511 0.68 MITF (0.32) MITF
SCHEMBL9769187 0.68 MITF (0.32) MITF
SCHEMBL14769651 0.68 AR (0.33) MITF
SCHEMBL21720376 0.68 MITF (0.32) MITF
SCHEMBL799935 0.68 MEN1 (0.32) MITF
SCHEMBL20121971 0.68 MITF (0.32) MITF
SCHEMBL23126509 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020198537-A1 MODULATORS OF MAS-RELATED G-PROTEIN RECEPTOR X4 AND RELATED PRODUCTS AND METHODS ESCIENT PHARMACEUTICALS, INC. (US) 2020-10-01 WO disclosed