Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MITF | O75030 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL47577 | 0.80 | MITF (0.36) | MITF | |
| SCHEMBL2307925 | 0.74 | — | — | |
| SCHEMBL420157 | 0.70 | TDP1 (0.53) | MITF | |
| SCHEMBL1799996 | 0.69 | — | — | |
| SCHEMBL10680944 | 0.69 | ALDH1A1 (0.32) | — | |
| SCHEMBL14769651 | 0.68 | AR (0.33) | MITF | |
| SCHEMBL11977475 | 0.68 | L3MBTL1 (0.32) | MITF | |
| SCHEMBL21720376 | 0.68 | MITF (0.32) | MITF | |
| SCHEMBL22480890 | 0.68 | MITF (0.32) | MITF | |
| SCHEMBL20121971 | 0.68 | MITF (0.32) | MITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4992534-A | Anticarcinogenic agents with better water solubility, low toxicity, absorption and stability | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-02-12 | — | — | US | disclosed |
| EP-0303269-A2 | 2'-Deoxy-5-fluorouridine derivatives, process for preparing the same and the use thereof | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1989-02-15 | — | — | EP | disclosed |