Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 4/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.35 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2821328 | 0.87 | GAA (0.53) | GAATSHRKMT2AMAPTALDH1A1 | |
| SCHEMBL13266120 | 0.84 | CYP4F2 (0.50) | ALOX5GAAALDH1A1HSD17B10 | |
| SCHEMBL13201688 | 0.81 | FFAR1 (0.44) | ALOX5 | |
| SCHEMBL1746736 | 0.80 | PCNA (0.44) | ALOX5SIRT2HSP90AB1NFKB1NFKB2 | |
| SCHEMBL172340 | 0.79 | KDM4E (0.43) | ALOX5SIRT2TSHRKMT2AMAPT | |
| SCHEMBL31432825 | 0.79 | ALOX5 (0.47) | ALOX5SIRT2KMT2APTPN1OR51E2 | |
| SCHEMBL5992538 | 0.76 | PTGS1 (0.44) | ALOX5SIRT2HSP90AB1NFKB1NFKB2 | |
| SCHEMBL11978546 | 0.76 | GAA (0.60) | NFKB1GAATSHRKMT2AMAPT | |
| SCHEMBL12294539 | 0.76 | GAA (0.47) | ALOX5NFKB1GAATSHRKMT2A | |
| SCHEMBL14191732 | 0.76 | GAA (0.47) | ALOX5NFKB1GAATSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8236390-B2 | Liquid-crystalline medium | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 2012-08-07 | — | — | US | disclosed |
| US-20100320420-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2010-12-23 | — | — | US | disclosed |
| US-7854970-B2 | Liquid-crystalline medium | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2010-12-21 | — | — | US | disclosed |
| US-20100188630-A1 | ELECTRO-OPTICAL LIGHT CONTROL ELEMENT, ELECTRO-OPTICAL DISPLAY AND CONTROL MEDIUM | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2010-07-29 | — | — | US | disclosed |
| US-7678432-B2 | Liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2010-03-16 | — | — | US | disclosed |
| US-20100051864-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GESELLSCHAFT (DE) | 2010-03-04 | — | — | US | disclosed |
| US-20080088789-A1 | Liquid-crystalline medium | MERCK PATENT GMBH | 2008-04-17 | — | — | US | disclosed |
| US-20070017151-A1 | Nucleophilic Acyl Substitutions of Acids or Esters Catalyzed by Oxometallic Complexes, and the Applications in Fabricating Biodiesel | NATIONAL TAIWAN NORMAL UNIVERSITY (TW) | 2007-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070017151-A1 | Nucleophilic Acyl Substitutions of Acids or Esters Catalyzed by Oxometallic Complexes, and the Applications in Fabricating Biodiesel | COASY, ACSL1, ACSL3 | ALOX5 341/4885SIRT2 1739/4885HSP90AB1 3472/4885 |
| US-20080088789-A1 | Liquid-crystalline medium | F12, CHRM1, NEFM | ALOX5 3635/4885SIRT2 3850/4885HSP90AB1 2308/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.