Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 6/20 | 0.38 |
| ▸ | RAB9A | P51151 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | RPS6KB2 | Q9UBS0 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12340307 | 0.84 | ALDH1A1 (0.40) | KDM4EALDH1A1HPGDALOX5HSD17B10 | |
| SCHEMBL10752939 | 0.84 | KDM4E (0.49) | KDM4EPOLBSIRT2NPC1RAB9A | |
| SCHEMBL25021957 | 0.83 | KDM4E (0.46) | KDM4EPOLBSIRT2NPC1RAB9A | |
| SCHEMBL7068865 | 0.81 | GAA (0.47) | KDM4EPOLBNPC1RAB9AALDH1A1 | |
| SCHEMBL31360 | 0.81 | GAA (0.47) | KDM4EPOLBNPC1RAB9AALDH1A1 | |
| SCHEMBL29350844 | 0.81 | GAA (0.47) | KDM4EPOLBNPC1RAB9AALDH1A1 | |
| SCHEMBL14791620 | 0.81 | NPC1 (0.35) | KDM4EPOLBNPC1RAB9AALDH1A1 | |
| SCHEMBL14791583 | 0.81 | NPC1 (0.40) | KDM4EPOLBNPC1RAB9AALDH1A1 | |
| SCHEMBL29142799 | 0.80 | KDM4E (0.47) | KDM4EPOLBNPC1RAB9AALDH1A1 | |
| SCHEMBL11979660 | 0.79 | ALOX5 (0.39) | SIRT2ALDH1A1ALOX5HSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8361568-B2 | Liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2013-01-29 | — | — | US | disclosed |
| US-20120305843-A1 | LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2012-12-06 | — | — | US | disclosed |
| US-20120261615-A1 | DEVICES FOR HIGH-FREQUENCY TECHNOLOGY, LIQUID-CRYSTALLINE MEDIA AND COMPOUNDS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2012-10-18 | — | — | US | disclosed |
| EP-2176376-B1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2012-09-19 | — | — | EP | disclosed |
| EP-1908811-B1 | Liquid crystalline medium | MERCK PATENT GMBH (DE) | 2012-08-29 | — | — | EP | disclosed |
| US-20120205583-A1 | COMPOUNDS FOR A LIQUID CRYSTAL MEDIUM AND HIGH-FREQUENCY COMPONENTS CONTAINING SAID LIQUID CRYSTAL MEDIUM | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2012-08-16 | — | — | US | disclosed |
| US-8236390-B2 | Liquid-crystalline medium | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 2012-08-07 | — | — | US | disclosed |
| WO-2012097858-A1 | POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | MERCK PATENT GMBH (DE) | 2012-07-26 | — | — | WO | disclosed |
| US-20120182200-A1 | COMPONENTS FOR HIGH-FREQUENCY TECHNOLOGY, AND LIQUID-CRYSTALLINE MEDIA | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2012-07-19 | — | — | US | disclosed |
| EP-2265692-B1 | THIOPHENE DERIVATIVES, AND LC MEDIA CONTAINING THE SAME | MERCK PATENT GMBH (DE) | 2012-07-04 | — | — | EP | disclosed |
| US-20070269614-A1 | Containing at least two nitrile-free mesogenic compounds, one of which contains rings including a phenyl ring llinked by at least one -CF2O- group; electrooptical dispalys | HECKMEIER MICHAEL | 2007-11-22 | — | — | US | disclosed |
| US-7294368-B2 | Liquid crystal composition for use in bistable liquid crystal devices | MERCK PATENT GMBH (DE) | 2007-11-13 | — | — | US | disclosed |
| EP-1565540-B1 | LIQUID CRYSTALLINE COMPOUNDS | MERCK PATENT GMBH (DE) | 2007-09-26 | — | — | EP | disclosed |
| EP-1563035-B1 | LIQUID CRYSTAL MEDIUM | MERCK PATENT GMBH (DE) | 2007-09-12 | — | — | EP | disclosed |
| US-20070176144-A1 | Liquid crystal composition for bistable liquid crystal devices | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2007-08-02 | — | — | US | disclosed |
| EP-1420057-B1 | Liquid crystalline medium | MERCK PATENT GMBH (DE) | 2007-05-16 | — | — | EP | disclosed |
| US-7189440-B2 | Liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2007-03-13 | — | — | US | disclosed |
| WO-2007017008-A1 | ELECTRO-OPTICAL LIGHT MODULATION ELEMENT, DISPLAY AND MEDIUM | MERCK PATENT GMBH (DE) | 2007-02-15 | — | — | WO | disclosed |
| WO-2007017180-A1 | LIQUID-CRYSTAL MEDIUM | MERCK PATENT GMBH (DE) | 2007-02-15 | — | — | WO | disclosed |
| EP-1746079-A2 | Fluorinated biphenyl compounds for use in liquid crystal compositions | Merck Patent GmbH (DE) | 2007-01-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120205583-A1 | COMPOUNDS FOR A LIQUID CRYSTAL MEDIUM AND HIGH-FREQUENCY COMPONENTS CONTAINING SAID LIQUID CRYSTAL MEDIUM | CHRM1, CXCR1, CCNL2 | KDM4E 4148/4885POLB 3392/4885SIRT2 3547/4885 |
| US-20120182200-A1 | COMPONENTS FOR HIGH-FREQUENCY TECHNOLOGY, AND LIQUID-CRYSTALLINE MEDIA | SFRP1, CRY1, MCM3 | KDM4E 4052/4885POLB 3505/4885SIRT2 2785/4885 |
| US-20120261615-A1 | DEVICES FOR HIGH-FREQUENCY TECHNOLOGY, LIQUID-CRYSTALLINE MEDIA AND COMPOUNDS | MCM5, MCM3, MCM7 | KDM4E 3780/4885POLB 2690/4885SIRT2 3247/4885 |
| US-20120305843-A1 | LIQUID CRYSTALLINE MEDIUM | NEFM, VIM, PLG | KDM4E 3357/4885POLB 439/4885SIRT2 2403/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.