Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.39 |
| ▸ | MAPK13 | O15264 | 3/20 | 0.38 |
| ▸ | MAPK12 | P53778 | 3/20 | 0.38 |
| ▸ | MAPK11 | Q15759 | 3/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CLK1 | P49759 | 1/20 | 0.38 |
| ▸ | CLK2 | P49760 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.38 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11979697 | 0.90 | TUBB4A (0.43) | ALDH1A1KDM4EHPGDHSD17B10MTNR1A | |
| SCHEMBL11979709 | 0.86 | CYP19A1 (0.48) | PDE10AMAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL11979704 | 0.85 | TUBB4A (0.43) | KDM4EHSD17B10PDE10AMAPK13MAPK12 | |
| SCHEMBL11979699 | 0.85 | TUBB4A (0.44) | PDE10AMAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL11979711 | 0.84 | PDE10A (0.39) | ALDH1A1KDM4EHPGDHSD17B10PDE10A | |
| SCHEMBL11979702 | 0.81 | PDE10A (0.39) | ALDH1A1KDM4EHPGDHSD17B10PDE10A | |
| SCHEMBL11978295 | 0.81 | PDE10A (0.37) | ALDH1A1KDM4EHPGDHSD17B10PDE10A | |
| SCHEMBL15975201 | 0.81 | PDE10A (0.38) | ALDH1A1KDM4EMTNR1AMTNR1BPDE10A | |
| SCHEMBL15975203 | 0.80 | PDE10A (0.38) | ALDH1A1KDM4EHPGDHSD17B10MTNR1A | |
| SCHEMBL3709862 | 0.79 | KDM4E (0.52) | ALDH1A1KDM4EHPGDHSD17B10MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8815903-B2 | Indole derivative and pharmacologically acceptable salt thereof | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2014-08-26 | — | — | US | disclosed |
| US-8815903-B2 | Indole derivative and pharmacologically acceptable salt thereof | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2014-08-26 | — | — | US | disclosed |
| WO-2012102255-A1 | INDOLE DERIVATIVE AND PHARMACOLOGICALLY ACCEPTABLE SALT OF SAME | キッセイ薬品工業株式会社 (JP) | 2012-08-02 | — | — | WO | disclosed |