Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5384052 | 0.83 | CYP3A4 (0.49) | KMT2AMEN1KIF11ALDH1A1CYP3A4 | |
| SCHEMBL6284986 | 0.74 | KMT2A (0.64) | KMT2AMEN1KIF11RAB9AALDH1A1 | |
| SCHEMBL28842285 | 0.73 | KMT2A (0.44) | KMT2AMEN1KIF11LMNATDP1 | |
| SCHEMBL658115 | 0.72 | CA1 (0.46) | RAB9AALDH1A1SMN1; SMN2MAPTTDP1 | |
| SCHEMBL23174993 | 0.72 | MEN1 (0.47) | KMT2AMEN1KIF11ALDH1A1PARP10 | |
| SCHEMBL9645558 | 0.72 | ALDH1A1 (0.49) | KMT2AMEN1KIF11RAB9AALDH1A1 | |
| SCHEMBL14839594 | 0.71 | ALDH1A1 (0.45) | KMT2AMEN1ALDH1A1CYP3A4SMN1; SMN2 | |
| SCHEMBL7460843 | 0.71 | TSHR (0.48) | KMT2AMEN1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL7473269 | 0.69 | EGFR (0.42) | KMT2AMEN1ALDH1A1CYP3A4SMN1; SMN2 | |
| SCHEMBL15057893 | 0.69 | GSK3B (0.61) | KMT2AMEN1KIF11ALDH1A1PARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8236985-B2 | Compounds and uses thereof | IMPERIAL INNOVATIONS LTD. (GB) | 2012-08-07 | — | — | US | disclosed |
| US-20100063144-A1 | COMPOUNDS AND USES THEREOF | IMPERIAL INNOVATIONS LTD (GB) | 2010-03-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100063144-A1 | COMPOUNDS AND USES THEREOF | HDAC1, HDAC11, HDAC2 | KMT2A 58/4885MEN1 1240/4885KIF11 4593/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.