SCHEMBL9645558

SCHEMBL9645558

CN(C)c1ccc(OC(N)=O)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.49
MAPT P10636 4/20 0.49
MEN1 O00255 3/20 0.49
KMT2A Q03164 3/20 0.49
TDP1 Q9NUW8 2/20 0.49
KDM4E B2RXH2 2/20 0.49
THRB P10828 1/20 0.49
GFER P55789 1/20 0.49
RAB9A P51151 4/20 0.48
HPGD P15428 2/20 0.48
TP53 P04637 3/20 0.47
NPC1 O15118 2/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
ESR2 Q92731 1/20 0.47
NOX1 Q9Y5S8 1/20 0.47
ALOX15 P16050 2/20 0.46
TSHR P16473 2/20 0.46
HSD17B10 Q99714 2/20 0.46
KIF11 P52732 1/20 0.46
CA12 O43570 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6284986 0.82 KMT2A (0.64) ALDH1A1MAPTMEN1KMT2ATDP1
SCHEMBL11841636 0.81 MAPT (0.56) ALDH1A1MAPTMEN1KMT2ATDP1
SCHEMBL2170993 0.81 LMNA (0.59) ALDH1A1MAPTMEN1KMT2ATDP1
Hydrochloric Acid SCHEMBL11841634 0.79 MAPT (0.54) ALDH1A1MAPTMEN1KMT2ATDP1
SCHEMBL9645546 0.79 MAPT (0.53) ALDH1A1MAPTMEN1KMT2ATDP1
SCHEMBL27636153 0.79 HSD17B3 (0.50) ALDH1A1MAPTMEN1KMT2ATDP1
SCHEMBL5519087 0.79 MAPT (0.57) ALDH1A1MAPTMEN1KMT2ATDP1
SCHEMBL27836538 0.79 MAPT (0.45) ALDH1A1MAPTMEN1KMT2ATDP1
SCHEMBL3129703 0.78 LRRK2 (0.48) MAPTMEN1KMT2ATDP1GFER
SCHEMBL472273 0.78 MAPT (0.47) ALDH1A1MAPTMEN1KMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115461352-A Immunomodulatory urea azalides 硕腾服务有限责任公司 2022-12-09 CN disclosed
EP-0283041-B1 DIRECT POSITIVE SILVER HALIDE PHOTOSENSITIVE MATERIAL AND METHOD FOR FORMING DIRECT POSITIVE IMAGE FUJI PHOTO FILM CO., LTD. (JP) 1992-10-07 EP disclosed
US-4952483-A NOVEL HYDRAZINE NUCLEATING AGENTS AND ACCELERATORS FUJI PHOTO FILM CO., LTD. (JP) 1990-08-28 US disclosed