Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | KIF11 | P52732 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.36 |
| ▸ | KLK1 | P06870 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28842285 | 0.84 | KMT2A (0.44) | MEN1KMT2AKIF11ELANEPARP10 | |
| SCHEMBL9542970 | 0.83 | ELANE (0.57) | MEN1KMT2AKIF11ELANEPARP10 | |
| SCHEMBL6284986 | 0.82 | KMT2A (0.64) | MEN1KMT2AKIF11ELANEPARP10 | |
| SCHEMBL13650268 | 0.81 | MEN1 (0.48) | MEN1KMT2AKIF11ELANEPARP10 | |
| SCHEMBL11052300 | 0.80 | KIF11 (0.47) | MEN1KMT2AKIF11ELANEPARP10 | |
| SCHEMBL11610897 | 0.79 | CES2 (0.42) | MEN1KMT2ACES2CES1ELANE | |
| SCHEMBL5562888 | 0.79 | MEN1 (0.47) | MEN1KMT2AKIF11ELANEPARP10 | |
| SCHEMBL1835776 | 0.79 | RAB9A (0.53) | MEN1KMT2AKIF11ELANETHRB | |
| SCHEMBL868628 | 0.79 | LMNA (0.57) | MEN1KMT2AELANEALDH1A1 | |
| SCHEMBL11375700 | 0.78 | PRSS1 (0.56) | MEN1KMT2AKIF11PRSS1TMPRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111936468-B | Compounds with anticancer activity | 协和麒麟株式会社 | 2024-03-08 | — | — | CN | disclosed |
| WO-2023236960-A1 | CARBOXAMIDE DERIVATIVE HAVING RSK INHIBITORY EFFECT, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USE THEREOF | 上海科恩泰生物医药科技有限公司 | 2023-12-14 | — | — | WO | disclosed |
| CN-117186098-A | Carboxamide derivative with RSK inhibition effect, pharmaceutical composition containing carboxamide derivative and application of carboxamide derivative | 上海科恩泰生物医药科技有限公司 | 2023-12-08 | — | — | CN | disclosed |
| WO-2023198195-A1 | CONJUGATE COMPRISING TOLL-LIKE RECEPTOR AGONIST | MABSOFT THERAPEUTICS (SHANGHAI) CO., LTD. (CN) | 2023-10-19 | — | — | WO | disclosed |
| CN-114845996-B | Benzene ring-containing compound and application thereof | 武汉朗来科技发展有限公司 | 2023-09-12 | — | — | CN | disclosed |
| WO-2023109954-A1 | TYK2 INHIBITORS AND COMPOSITIONS AND METHODS THEREOF | LYNK PHARMACEUTICALS CO. LTD. (CN) | 2023-06-22 | — | — | WO | disclosed |
| WO-2023109120-A1 | TYK2 INHIBITORS AND COMPOSITIONS AND METHODS THEREOF | LYNK PHARMACEUTICALS CO. LTD. (CN) | 2023-06-22 | — | — | WO | disclosed |
| WO-2023108536-A1 | TYK2 INHIBITORS AND COMPOSITIONS AND METHODS THEREOF | LYNK PHARMACEUTICALS CO. LTD. (CN) | 2023-06-22 | — | — | WO | disclosed |
| CN-114845996-A | Compound containing benzene ring and application thereof | 武汉朗来科技发展有限公司 | 2022-08-02 | — | — | CN | disclosed |
| CN-109563043-B | Substituted pyridines as inhibitors of DNMT1 | 葛兰素史密斯克莱知识产权发展有限公司 | 2022-05-31 | — | — | CN | disclosed |
| CN-114502534-A | BET degradant | 协和麒麟株式会社 | 2022-05-13 | — | — | CN | disclosed |
| CN-113620950-A | Carboxamide derivatives useful as RSK inhibitors | 凤凰分子设计公司 | 2021-11-09 | — | — | CN | disclosed |
| CN-109071542-B | Carboxamide derivatives useful as RSK inhibitors | 凤凰分子设计公司 | 2021-07-20 | — | — | CN | disclosed |
| WO-2021065980-A1 | BET DEGRADER | 協和キリン株式会社 | 2021-04-08 | — | — | WO | disclosed |
| CN-111936468-A | Compounds with anti-cancer activity | 协和麒麟株式会社 | 2020-11-13 | — | — | CN | disclosed |
| CN-109071542-A | CARBOXAMIDE DERIVATIVES USEFUL AS RSK INHIBITORS | 凤凰分子设计公司 | 2018-12-21 | — | — | CN | disclosed |