SCHEMBL11986096

SCHEMBL11986096

C=C(C(=O)OCOC(=O)Oc1ccc(C(=O)Oc2ccc3c(c2)C(C)c2cc(OC(=O)c4ccc(OC(=O)OCOC(=O)C(=C)C(F)(F)F)cc4)ccc2-3)cc1)C(F)(F)F

nearest known ligand 0.34

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.34
KMT2A Q03164 4/20 0.34
MEN1 O00255 3/20 0.34
ELANE P08246 1/20 0.31
PRSS1 P07477 2/20 0.31
ACR P10323 2/20 0.31
NR1H4 Q96RI1 1/20 0.31
HSD17B10 Q99714 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11986089 0.89 MAPT (0.33) MAPTKMT2AMEN1ELANEPRSS1
SCHEMBL11986054 0.88 POLB (0.38) MAPTKMT2AMEN1ELANEPRSS1
SCHEMBL14088599 0.84 HTT (0.45) MAPTKMT2AMEN1PRSS1ACR
SCHEMBL11986090 0.81 THRB (0.34) MAPTKMT2AMEN1PRSS1ACR
SCHEMBL13289632 0.80 POLB (0.40) MAPTKMT2AMEN1ELANEPRSS1
SCHEMBL2606426 0.79 LMNA (0.36) ELANE
SCHEMBL14088601 0.78 THRA (0.37) MAPTKMT2AMEN1SMN1; SMN2TDP1
SCHEMBL13226590 0.77 POLB (0.41) MAPTKMT2AMEN1ELANEHSD17B10
SCHEMBL13226606 0.77 POLB (0.41) MAPTKMT2AMEN1ELANEHSD17B10
SCHEMBL11986062 0.77 POLB (0.41) MAPTKMT2AMEN1ELANEHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8246855-B2 Polymerizable liquid crystal composition and optically anisotropic film using the same JNC CORPORATION (JP) 2012-08-21 US disclosed
US-20100051866-A1 Polymerizable liquid crystal composition and optically anisotropic film using the same JNC PETROCHEMICAL CORPORATION (JP) 2010-03-04 US disclosed