SCHEMBL11986142

SCHEMBL11986142

C=CC(=O)OCOc1ccc(CCC(=O)Oc2ccc(C(c3ccc(OC(=O)CCc4ccc(OCOC(=O)C=C)cc4)cc3)(C(F)(F)F)C(F)(F)F)cc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
THRB P10828 3/20 0.42
KMT2A Q03164 4/20 0.37
FFAR1 O14842 5/20 0.35
FFAR4 Q5NUL3 3/20 0.35
HPGD P15428 1/20 0.33
PPARG P37231 1/20 0.32
PPARD Q03181 1/20 0.32
PPARA Q07869 1/20 0.32
MEN1 O00255 1/20 0.32
MAOB P27338 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14117093 0.95 THRB (0.41) THRBKMT2AFFAR1FFAR4PPARG
SCHEMBL12769637 0.91 THRB (0.48) THRBKMT2AFFAR1FFAR4PPARG
SCHEMBL12769620 0.89 THRB (0.43) THRBKMT2AFFAR1HPGDMEN1
SCHEMBL12769596 0.89 KMT2A (0.43) THRBKMT2AHPGDMEN1MAOB
SCHEMBL12769628 0.89 THRB (0.43) THRBKMT2AFFAR1MEN1
SCHEMBL12154226 0.89 THRB (0.52) THRBKMT2AFFAR1FFAR4HPGD
SCHEMBL14117062 0.87 THRB (0.44) THRBKMT2AHPGDPPARGPPARD
SCHEMBL11986145 0.85 FFAR1 (0.34) THRBKMT2AFFAR1FFAR4
SCHEMBL14117064 0.85 THRB (0.45) THRBKMT2AFFAR1HPGDPPARG
SCHEMBL15582417 0.85 THRB (0.49) THRBKMT2AFFAR1FFAR4HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160122651-A1 LIQUID CRYSTAL ALIGNMENT AGENT, LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT CHI MEI CORPORATION (TW) 2016-05-05 US disclosed
US-9315728-B2 Polymerizable liquid crystal composition and homogeneous-aligned liquid crystal film JNC CORPORATION (JP) 2016-04-19 US disclosed
US-20150361345-A1 LIQUID CRYSTAL ALIGNMENT AGENT, LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT CHI MEI CORPORATION (TW) 2015-12-17 US disclosed
US-20150177567-A1 LIQUID CRYSTAL ALIGNMENT AGENT, LIQUID CRYSTAL ALIGNMENT FILM AND LIQUID CRYSTAL DISPLAY ELEMENT HAVING THEREOF CHI MEI CORPORATION (TW) 2015-06-25 US disclosed
US-8419973-B2 Polymerizable liquid crystal composition and homeotropically-aligned liquid crystal film JNC CORPORATION (JP) 2013-04-16 US disclosed
US-8246855-B2 Polymerizable liquid crystal composition and optically anisotropic film using the same JNC CORPORATION (JP) 2012-08-21 US disclosed
US-RE42221-E1 Polymerizable liquid crystal composition and polymer thereof CHISSO CORPORATION (JP) 2011-03-15 US disclosed
US-20100151154-A1 Polymerizable liquid crystal composition and homeotropically-aligned liquid crystal film CHISSO CORPORATION 2010-06-17 US disclosed
US-20100143612-A1 Polymerizable liquid crystal composition and homogeneous-aligned liquid crystal film CHISSO CORPORATION 2010-06-10 US disclosed
US-20100051866-A1 Polymerizable liquid crystal composition and optically anisotropic film using the same JNC PETROCHEMICAL CORPORATION (JP) 2010-03-04 US disclosed