SCHEMBL11986145

SCHEMBL11986145

C=CC(=O)OCOc1ccc(CCC(=O)Oc2ccc(C(c3ccc(OC(=O)CCc4ccc(OCOC(=O)C=C)cc4F)cc3)(C(F)(F)F)C(F)(F)F)cc2)c(F)c1

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 14/20 0.34
THRB P10828 3/20 0.32
FFAR4 Q5NUL3 1/20 0.32
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12154299 0.90 FFAR1 (0.38) FFAR1THRBFFAR4KMT2A
SCHEMBL15582418 0.86 THRB (0.38) FFAR1THRBFFAR4
SCHEMBL11986142 0.85 THRB (0.42) FFAR1THRBFFAR4KMT2A
SCHEMBL11986143 0.85 FFAR1 (0.35) FFAR1FFAR4KMT2A
SCHEMBL11986161 0.84 PKM (0.36) FFAR1THRBFFAR4KMT2A
SCHEMBL12567700 0.83 PPARD (0.35) FFAR1FFAR4
SCHEMBL13664618 0.83 AKR1C3 (0.35) FFAR1THRBFFAR4
SCHEMBL11986132 0.82 CYP11B1 (0.34) THRBKMT2A
SCHEMBL12769579 0.82 PPARD (0.34) FFAR1THRBFFAR4KMT2A
SCHEMBL14117093 0.81 THRB (0.41) FFAR1THRBFFAR4KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9315728-B2 Polymerizable liquid crystal composition and homogeneous-aligned liquid crystal film JNC CORPORATION (JP) 2016-04-19 US disclosed
US-8419973-B2 Polymerizable liquid crystal composition and homeotropically-aligned liquid crystal film JNC CORPORATION (JP) 2013-04-16 US disclosed
US-8246855-B2 Polymerizable liquid crystal composition and optically anisotropic film using the same JNC CORPORATION (JP) 2012-08-21 US disclosed
US-20100151154-A1 Polymerizable liquid crystal composition and homeotropically-aligned liquid crystal film CHISSO CORPORATION 2010-06-17 US disclosed
US-20100143612-A1 Polymerizable liquid crystal composition and homogeneous-aligned liquid crystal film CHISSO CORPORATION 2010-06-10 US disclosed
US-20100051866-A1 Polymerizable liquid crystal composition and optically anisotropic film using the same JNC PETROCHEMICAL CORPORATION (JP) 2010-03-04 US disclosed