Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | THRB | P10828 | 3/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.33 |
| ▸ | PTPRC | P08575 | 1/20 | 0.32 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | PTPRB | P23467 | 1/20 | 0.32 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.32 |
| ▸ | CDC25A | P30304 | 1/20 | 0.32 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11986142 | 0.89 | THRB (0.42) | KMT2ATHRBMAOBMEN1HPGD | |
| SCHEMBL14117093 | 0.84 | THRB (0.41) | KMT2ATHRBMEN1L3MBTL1LMNA | |
| SCHEMBL11986138 | 0.84 | PRSS1 (0.40) | KMT2ATHRBMAOBMEN1L3MBTL1 | |
| SCHEMBL12769579 | 0.83 | PPARD (0.34) | KMT2ATHRBSMN1; SMN2L3MBTL1 | |
| SCHEMBL11986146 | 0.82 | KMT2A (0.43) | KMT2ATHRBMAOBMEN1LMNA | |
| SCHEMBL14117060 | 0.81 | L3MBTL1 (0.33) | THRBSMN1; SMN2L3MBTL1LMNA | |
| SCHEMBL12769600 | 0.80 | GAA (0.42) | KMT2ATHRBCYP19A1SMN1; SMN2ASAH1 | |
| SCHEMBL12769637 | 0.80 | THRB (0.48) | KMT2ATHRBMEN1L3MBTL1LMNA | |
| SCHEMBL14117057 | 0.80 | PPARD (0.38) | HPGDL3MBTL1LMNA | |
| SCHEMBL11986145 | 0.79 | FFAR1 (0.34) | KMT2ATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE42221-E1 | Polymerizable liquid crystal composition and polymer thereof | CHISSO CORPORATION (JP) | 2011-03-15 | — | — | US | disclosed |
| US-7393569-B2 | Hexafluoroisopropylidenebis- and sulfonylbis-(phenoxycarbonylphenoxyalkyl acrylates); hexafluoroisopropylidenebis- and sulfonylbis-(phenoxycarbonylphenoxyalkyloxetanes; stabilizes polymerizable liquid crystal compositions for a long time and controls the alignment of liquid crystal molecules | CHISSO CORPORATION (JP) | 2008-07-01 | — | — | US | disclosed |