Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13254368 | 0.86 | TDP1 (0.40) | TDP1SMN1; SMN2SLC22A6TSHRTP53 | |
| Isocitric Acid SCHEMBL27894954 | 0.82 | TDP1 (0.68) | TDP1SMN1; SMN2SLC22A6MAPTGABRR1 | |
| Isocitric Acid SCHEMBL29645996 | 0.82 | TDP1 (0.68) | TDP1SMN1; SMN2SLC22A6MAPTGABRR1 | |
| Isocitric Acid SCHEMBL30700829 | 0.82 | TDP1 (0.68) | TDP1SMN1; SMN2SLC22A6MAPTGABRR1 | |
| Isocitric Acid SCHEMBL6249818 | 0.82 | TDP1 (0.68) | TDP1SMN1; SMN2SLC22A6MAPTGABRR1 | |
| Isocitrate SCHEMBL1289944 | 0.82 | TDP1 (0.68) | TDP1SMN1; SMN2SLC22A6MAPTGABRR1 | |
| Isocitric Acid SCHEMBL12927570 | 0.82 | TDP1 (0.68) | TDP1SMN1; SMN2SLC22A6MAPTGABRR1 | |
| Isocitrate SCHEMBL8373 | 0.82 | TDP1 (0.68) | TDP1SMN1; SMN2SLC22A6MAPTGABRR1 | |
| Isocitric Acid SCHEMBL2794437 | 0.82 | TDP1 (0.68) | TDP1SMN1; SMN2SLC22A6MAPTGABRR1 | |
| SCHEMBL9911940 | 0.82 | TDP1 (0.37) | TDP1SMN1; SMN2TSHRTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9884937-B2 | Polymer compositions and methods | SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) | 2018-02-06 | — | — | US | disclosed |
| US-9850345-B2 | Polycarbonate polyol compositions and methods | SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) | 2017-12-26 | — | — | US | disclosed |
| US-9834710-B2 | Adhesive compositions and methods | SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) | 2017-12-05 | — | — | US | disclosed |
| US-20170051106-A1 | POLYCARBONATE POLYOL COMPOSITIONS AND METHODS | SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) | 2017-02-23 | — | — | US | disclosed |
| US-20170022319-A1 | ALIPHATIC POLYCARBONATE POLYOL COMPOSITIONS | SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) | 2017-01-26 | — | — | US | disclosed |
| US-9512259-B2 | High strength polyurethane foam compositions and methods | NOVOMER, INC. (US) | 2016-12-06 | — | — | US | disclosed |
| US-20160319064-A1 | POLYMER COMPOSITIONS AND METHODS | SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) | 2016-11-03 | — | — | US | disclosed |
| US-9453100-B2 | Polymer compositions and methods | NOVOMER, INC. (US) | 2016-09-27 | — | — | US | disclosed |
| US-20160264728-A1 | POLYCARBONATE POLYOL COMPOSITIONS AND METHODS | SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) | 2016-09-15 | — | — | US | disclosed |
| US-9399701-B2 | Polymer compositions and methods | NOVOMER, INC. (US) | 2016-07-26 | — | — | US | disclosed |
| US-20140024795-A1 | ALIPHATIC POLYCARBONATE POLYOLS CONTAINING SILYL GROUPS | NOVOMER, INC. (US) | 2014-01-23 | — | — | US | disclosed |
| US-20130281633-A1 | POLYMER COMPOSITIONS AND METHODS | NOVOMER, INC. (US) | 2013-10-24 | — | — | US | disclosed |
| US-20130274401-A1 | ADHESIVE COMPOSITIONS AND METHODS | NOVOMER, INC. (US) | 2013-10-17 | — | — | US | disclosed |
| US-20130244864-A1 | POLYCARBONATE POLYOL COMPOSITIONS AND METHODS | NOVOMER, INC. (US) | 2013-09-19 | — | — | US | disclosed |
| US-20130172482-A1 | POLYMER COMPOSITIONS AND METHODS | NOVOMER, INC. (US) | 2013-07-04 | — | — | US | disclosed |
| US-8470956-B2 | Polycarbonate polyol compositions and methods | NOVOMER, INC. (US) | 2013-06-25 | — | — | US | disclosed |
| US-20130066044-A1 | POLYCARBONATE POLYOL COMPOSITIONS AND METHODS | NOVOMER, INC. (US) | 2013-03-14 | — | — | US | disclosed |
| US-8247520-B2 | Polycarbonate polyol compositions and methods | NOVOMER, INC. (US) | 2012-08-21 | — | — | US | disclosed |
| US-20110230580-A1 | POLYCARBONATE POLYOL COMPOSITIONS AND METHODS | Novomer, Inc (US) | 2011-09-22 | — | — | US | disclosed |
| US-20100184643-A1 | Methods and Compounds Regulating the Erythroid Response to Iron Deficiency | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2010-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110230580-A1 | POLYCARBONATE POLYOL COMPOSITIONS AND METHODS | PARG, PUF60, PICALM | TDP1 2850/4885SMN1; SMN2 4396/4885SLC22A6 3039/4885 |
| US-20100184643-A1 | Methods and Compounds Regulating the Erythroid Response to Iron Deficiency | EPOR, MPL, MCL1 | TDP1 4797/4885SMN1; SMN2 4488/4885SLC22A6 2478/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.