SCHEMBL11986249

SCHEMBL11986249

CC(O)COC(=O)OCC1CCC(COC(=O)OCC(C)O)CC1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.37
SLC1A3 P43003 2/20 0.33
SLC1A2 P43004 2/20 0.33
SLC1A1 P43005 2/20 0.33
LMNA P02545 2/20 0.33
PTGIR P43119 1/20 0.31
MEN1 O00255 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2C9 P11712 1/20 0.31
NFKB1 P19838 1/20 0.31
PTGS1 P23219 1/20 0.31
APEX1 P27695 1/20 0.31
THPO P40225 1/20 0.31
PMP22 Q01453 1/20 0.31
KMT2A Q03164 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
ACACB O00763 3/20 0.31
TSHR P16473 1/20 0.31
MAPK1 P28482 1/20 0.30
FYN P06241 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8293492 0.86 LMNA (0.41) SLC1A3SLC1A2SLC1A1LMNAPTGIR
SCHEMBL12015336 0.85
SCHEMBL1007670 0.81 MAPT (0.48) MAPTLMNAMEN1CYP3A4CYP2C9
SCHEMBL28519812 0.81 MAPT (0.48) MAPTLMNAMEN1CYP3A4CYP2C9
SCHEMBL1444506 0.81 LMNA (0.43) SLC1A3SLC1A2SLC1A1LMNAPTGIR
SCHEMBL3485368 0.80 LMNA (0.38) SLC1A3SLC1A2SLC1A1LMNAMEN1
SCHEMBL4200004 0.78 LMNA (0.46) SLC1A3SLC1A2SLC1A1LMNAMEN1
SCHEMBL698072 0.77
SCHEMBL11146357 0.77 SLC1A3 (0.38) SLC1A3SLC1A2SLC1A1LMNAPTGIR
SCHEMBL1439642 0.75 ALDH1A1 (0.59) MAPTLMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160264728-A1 POLYCARBONATE POLYOL COMPOSITIONS AND METHODS SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) 2016-09-15 US disclosed
US-9376531-B2 Polycarbonate polyol compositions and methods NOVOMER, INC. (US) 2016-06-28 US disclosed
US-20150299386-A1 POLYCARBONATE POLYOL COMPOSITIONS AND METHODS SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) 2015-10-22 US disclosed
US-8921508-B2 Polycarbonate polyol compositions and methods NOVOMER, INC. (US) 2014-12-30 US disclosed
US-20140046008-A1 POLYCARBONATE POLYOL COMPOSITIONS AND METHODS NOVOMER, INC. (US) 2014-02-13 US disclosed
US-20130244864-A1 POLYCARBONATE POLYOL COMPOSITIONS AND METHODS NOVOMER, INC. (US) 2013-09-19 US disclosed
US-8470956-B2 Polycarbonate polyol compositions and methods NOVOMER, INC. (US) 2013-06-25 US disclosed
US-20130066044-A1 POLYCARBONATE POLYOL COMPOSITIONS AND METHODS NOVOMER, INC. (US) 2013-03-14 US disclosed
US-8247520-B2 Polycarbonate polyol compositions and methods NOVOMER, INC. (US) 2012-08-21 US disclosed
US-20110230580-A1 POLYCARBONATE POLYOL COMPOSITIONS AND METHODS Novomer, Inc (US) 2011-09-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110230580-A1 POLYCARBONATE POLYOL COMPOSITIONS AND METHODS PARG, PUF60, PICALM MAPT 3045/4885SLC1A3 3127/4885SLC1A2 3908/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.