Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.30 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.30 |
| ▸ | MC3R | P41968 | 1/20 | 0.30 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.30 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.30 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10039865 | 0.74 | PIK3CD (0.30) | PIK3CDPOLBADORA3CNR1ACHE | |
| SCHEMBL20011291 | 0.71 | GDA (0.31) | ALDH1A1TSHRGDA | |
| SCHEMBL31685444 | 0.68 | ALDH1A1 (0.38) | ALDH1A1TSHRPIK3CDPOLBADORA3 | |
| SCHEMBL15071610 | 0.67 | MAPT (0.30) | — | |
| SCHEMBL15071608 | 0.61 | KDM4E (0.37) | — | |
| SCHEMBL24611645 | 0.59 | — | — | |
| SCHEMBL13177050 | 0.58 | GDA (0.32) | ALDH1A1TSHRGDA | |
| SCHEMBL19090548 | 0.58 | BRD4 (0.39) | ALDH1A1TSHRADORA2AADORA2B | |
| SCHEMBL10070690 | 0.57 | — | — | |
| SCHEMBL14902045 | 0.56 | PNP (0.46) | ALDH1A1TSHRPIK3CDPOLBADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8247445-B2 | Platinum complexes and methods of use | UNIVERSITY OF SOUTH FLORIDA (US) | 2012-08-21 | — | — | US | disclosed |
| US-7759510-B2 | Platinum complexes and methods of use | UNIVERSITY OF SOUTH FLORIDA (US) | 2010-07-20 | — | — | US | disclosed |
| US-20090285884-A1 | Platinum Complexes and Methods of Use | UNIVERSITY OF SOUTH FLORIDA (US) | 2009-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090285884-A1 | Platinum Complexes and Methods of Use | CXCR3, POLI, ZC3HAV1 | ALDH1A1 1958/4885TSHR 3268/4885PIK3CD 3444/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.