Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.40 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | PRKG1 | Q13976 | 1/20 | 0.37 |
| ▸ | SLC6A7 | Q99884 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 2/20 | 0.36 |
| ▸ | AKT3 | Q9Y243 | 2/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | AKT2 | P31751 | 1/20 | 0.36 |
| ▸ | KIT | P10721 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2248888 | 1.00 | MMP1 (0.42) | MMP1MMP2MMP8PANK3GRM1 | |
| SCHEMBL2242116 | 1.00 | MMP1 (0.42) | MMP1MMP2MMP8PANK3GRM1 | |
| SCHEMBL8271398 | 1.00 | MMP1 (0.42) | MMP1MMP2MMP8PANK3GRM1 | |
| SCHEMBL8273020 | 1.00 | MMP1 (0.42) | MMP1MMP2MMP8PANK3GRM1 | |
| SCHEMBL13876661 | 0.91 | PANK3 (0.39) | PANK3GRM1HDAC1CHRM4ENPP2 | |
| SCHEMBL2252819 | 0.91 | GRM1 (0.41) | PANK3GRM1HDAC1CHRM4ENPP2 | |
| SCHEMBL2246283 | 0.91 | GRM1 (0.41) | PANK3GRM1HDAC1CHRM4ENPP2 | |
| SCHEMBL2245815 | 0.87 | HDAC1 (0.42) | MMP1MMP2MMP8GRM1HDAC1 | |
| SCHEMBL2250775 | 0.87 | CHRM2 (0.48) | MMP1MMP2MMP8PANK3CHRM2 | |
| SCHEMBL2244374 | 0.86 | MMP2 (0.46) | MMP1MMP2MMP8HDAC1SLC6A7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8247437-B2 | N-hydroxyamide derivatives and use thereof | MERCK SERONO SA (CH) | 2012-08-21 | — | — | US | disclosed |
| US-20110263628-A1 | N-HYDROXYAMIDE DERIVATIVES AND USE THEREOF | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2011-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110263628-A1 | N-HYDROXYAMIDE DERIVATIVES AND USE THEREOF | HNMT, HCAR2, HPGD | MMP1 812/4885MMP2 1413/4885MMP8 438/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.