Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 4/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31317020 | 1.00 | HTT (0.46) | HTTKMT2AMEN1HSD17B10POLB | |
| Water SCHEMBL29974467 | 0.98 | HTT (0.45) | HTTKMT2AMEN1HSD17B10POLB | |
| Water SCHEMBL28877782 | 0.98 | HTT (0.45) | HTTKMT2AMEN1HSD17B10POLB | |
| SCHEMBL1164963 | 0.78 | HTT (0.37) | HTTKMT2AMEN1HSD17B10POLB | |
| SCHEMBL2698210 | 0.78 | DHODH (0.36) | HTTKMT2AMEN1HSD17B10POLB | |
| SCHEMBL8485465 | 0.78 | ALDH1A1 (0.35) | HTTKMT2AMEN1HSD17B10GAA | |
| SCHEMBL4371544 | 0.78 | NOS3 (0.39) | HTTKMT2AMEN1HSD17B10GAA | |
| SCHEMBL15167171 | 0.78 | PLAU (0.46) | HTTKMT2AMEN1GAAPLAU | |
| SCHEMBL9034534 | 0.77 | GAA (0.46) | HTTKMT2AMEN1HSD17B10POLB | |
| SCHEMBL12909531 | 0.77 | KMT2A (0.50) | HTTKMT2AMEN1HSD17B10POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118955469-A | Pyrazole alcohol compound as well as preparation method and application thereof | 安徽中医药大学 | 2024-11-15 | — | — | CN | claimed |
| CN-118126023-B | Pyrazole amide compound as well as preparation method and application thereof | 安徽中医药大学 | 2025-04-11 | — | — | CN | disclosed |
| CN-118955469-A | Pyrazole alcohol compound as well as preparation method and application thereof | 安徽中医药大学 | 2024-11-15 | — | — | CN | disclosed |
| CN-118791428-A | Method for preparing 3-chloro-2-hydrazinopyridine | 利尔化学股份有限公司 | 2024-10-18 | — | — | CN | disclosed |
| CN-118126023-A | Pyrazole amide compound as well as preparation method and application thereof | 安徽中医药大学 | 2024-06-04 | — | — | CN | disclosed |
| CN-106831705-B | Synthesis method of pyridyl pyrazolidone carboxylic ester compound | 江苏扬农化工集团有限公司 | 2021-02-19 | — | — | CN | disclosed |
| CN-111072630-A | Preparation method and application of bromopyrazole compound intermediate | 东南大学 | 2020-04-28 | — | — | CN | disclosed |
| EP-2837627-B1 | AMIDOPYRIDINE DERIVATIVE, AND USE THEREOF | MITSUBISHI TANABE PHARMA CORP (JP) | 2017-01-18 | — | — | EP | disclosed |
| US-9527859-B2 | Amidopyridine derivative and use thereof | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2016-12-27 | — | — | US | disclosed |
| US-9150555-B2 | Amide derivative and use thereof | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2015-10-06 | — | — | US | disclosed |
| WO-2009117421-A2 | HETEROCYCLIC MODULATORS OF GPR119 FOR TREATMENT OF DISEASE | KALYPSYS, INC. (US) | 2009-09-24 | — | — | WO | disclosed |
| WO-2007062678-A1 | PHENOXYACETIC ACID DERIVATIVES AS CRTH2 RECEPTOR LIGANDS | 7TM PHARMA A/S (DK) | 2007-06-07 | — | — | WO | disclosed |
| US-6551682-B1 | Proper tracking error signals to be adapted to high density information recording and has various characteristics | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 2003-04-22 | — | — | US | disclosed |
| EP-0930300-B1 | Process for preparing (poly)chloropyridines | DAICEL CHEM (JP) | 2003-01-22 | — | — | EP | disclosed |
| US-5977370-A | Process for preparing pyridine chloride | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1999-11-02 | — | — | US | disclosed |
| EP-0930300-A1 | Process for preparing (poly)chloropyridines | DAICEL CHEMICAL INDUSTRIES, Ltd. (JP) | 1999-07-21 | — | — | EP | disclosed |
| US-4772312-A | PRE-AND POSTEMERGENCE | BAYER AKTIENGESELLSCHAFT (DE) | 1988-09-20 | — | — | US | disclosed |
| EP-0207285-A1 | 5-Amino-1-pyridyl-pyrazoles | BAYER AG (DE) | 1987-01-07 | — | — | EP | disclosed |
| EP-0205024-A2 | 5-Amino-4-heterocyclyl-1-pyridyl-pyrazoles | BAYER AG (DE) | 1986-12-17 | — | — | EP | disclosed |
| EP-0205021-A2 | 5-Amino-4-cyano-1-pyridyl pyrazoles | BAYER AG (DE) | 1986-12-17 | — | — | EP | disclosed |