SCHEMBL11991074

SCHEMBL11991074

COC(=O)c1ccc(P(=O)(c2ccc(C(=O)OC)cc2)c2ccc3ccccc3c2-c2c(P(=O)(c3ccc(C)cc3)c3ccc(C)cc3)ccc3ccccc23)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.49
MEN1 O00255 5/20 0.43
KMT2A Q03164 5/20 0.43
KDM4A O75164 1/20 0.43
CTDSP1 Q9GZU7 1/20 0.43
KDM4C Q9H3R0 1/20 0.43
MAPT P10636 4/20 0.42
TP53 P04637 2/20 0.42
ALDH1A1 P00352 5/20 0.42
NPC1 O15118 3/20 0.41
RAB9A P51151 3/20 0.41
KDM4E B2RXH2 5/20 0.41
GPR84 Q9NQS5 1/20 0.41
KCNJ11 Q14654 1/20 0.40
TSHR P16473 2/20 0.40
SCN2A Q99250 1/20 0.39
HPGD P15428 3/20 0.39
NPSR1 Q6W5P4 1/20 0.39
CYP1A2 P05177 1/20 0.38
CYP2C9 P11712 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16301846 0.95 KDM4E (0.44) TDP1MEN1KMT2AMAPTTP53
SCHEMBL10710567 0.85 MAPT (0.39) TDP1MEN1KMT2AKDM4ACTDSP1
SCHEMBL12336891 0.83 MAPT (0.43) MEN1KMT2AKDM4ACTDSP1KDM4C
SCHEMBL4401115 0.83 MAPT (0.43) MEN1KMT2AKDM4ACTDSP1KDM4C
SCHEMBL4403131 0.83 MAPT (0.43) MEN1KMT2AKDM4ACTDSP1KDM4C
SCHEMBL31296445 0.81 MAPT (0.46) TDP1MEN1KMT2AKDM4ACTDSP1
SCHEMBL11991718 0.76 MAPT (0.49) TDP1MEN1KMT2AMAPTNPC1
SCHEMBL11991107 0.76 KCNJ11 (0.39) MEN1KMT2AKDM4ACTDSP1KDM4C
SCHEMBL17747337 0.74 HKDC1 (0.32) MEN1KMT2AKDM4ACTDSP1KDM4C
SCHEMBL6053640 0.74 KMT2A (0.43) MEN1KMT2AMAPTALDH1A1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120211082-A1 PHOTOELECTRIC CONVERSION DEVICE AND SOLAR CELL USING THE SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2012-08-23 US disclosed