SCHEMBL4401115

SCHEMBL4401115

Cc1ccc(P(=O)(c2ccccc2)c2ccc3ccccc3c2-c2c(P(=O)(c3ccccc3)c3ccc(C)cc3)ccc3ccccc23)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.43
POLB P06746 2/20 0.43
KDM4E B2RXH2 1/20 0.43
RAB9A P51151 4/20 0.40
NPC1 O15118 3/20 0.40
HPGD P15428 1/20 0.40
NPSR1 Q6W5P4 3/20 0.39
WDR5 P61964 1/20 0.38
MEN1 O00255 4/20 0.37
KMT2A Q03164 4/20 0.37
ALDH1A1 P00352 1/20 0.37
GAA P10253 1/20 0.37
KDM4A O75164 1/20 0.37
CTDSP1 Q9GZU7 1/20 0.37
KDM4C Q9H3R0 1/20 0.37
GPR84 Q9NQS5 1/20 0.36
LMNA P02545 2/20 0.36
TSHR P16473 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
HKDC1 Q2TB90 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12336891 1.00 MAPT (0.43) MAPTPOLBKDM4ERAB9ANPC1
SCHEMBL4403131 1.00 MAPT (0.43) MAPTPOLBKDM4ERAB9ANPC1
SCHEMBL10710567 0.97 MAPT (0.39) MAPTPOLBKDM4ERAB9ANPC1
SCHEMBL29382484 0.90 WDR5 (0.44) MAPTPOLBKDM4ENPSR1WDR5
SCHEMBL132989 0.90 WDR5 (0.44) MAPTPOLBKDM4ENPSR1WDR5
SCHEMBL31296445 0.88 MAPT (0.46) MAPTPOLBKDM4ERAB9ANPC1
SCHEMBL11991107 0.86 KCNJ11 (0.39) MAPTPOLBKDM4ERAB9ANPC1
SCHEMBL12336914 0.85 MAPT (0.42) MAPTPOLBKDM4ERAB9ANPC1
SCHEMBL11991070 0.84 WDR5 (0.38) MAPTPOLBRAB9ANPC1HPGD
SCHEMBL17747337 0.84 HKDC1 (0.32) MAPTPOLBKDM4ERAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1675930-B1 NEW MATERIALS FOR ELECTROLUMINESCENCE AND THE UTILIZATION THEREOF MERCK PATENT GMBH (DE) 2018-05-30 EP disclosed
US-8173276-B2 Materials for electroluminescence and the utilization thereof MERCK PATENT GMBH (DE) 2012-05-08 US disclosed
US-8173276-B2 Materials for electroluminescence and the utilization thereof MERCK PATENT GMBH (DE) 2012-05-08 US disclosed
US-20100102305-A1 MATERIALS FOR ELECTROLUMINESCENCE AND THE UTILIZATION THEREOF MERCK PATENT GMBH (DE) 2010-04-29 US disclosed
US-20100102305-A1 MATERIALS FOR ELECTROLUMINESCENCE AND THE UTILIZATION THEREOF MERCK PATENT GMBH (DE) 2010-04-29 US disclosed
US-7659540-B2 Materials for electroluminescence and the utilization thereof MERCK PATENT GMBH (DE) 2010-02-09 US disclosed
US-7659540-B2 Materials for electroluminescence and the utilization thereof MERCK PATENT GMBH (DE) 2010-02-09 US disclosed
US-20070080343-A1 New materials for electroluminescence and the utilization thereof MERCK PATENT GMBH (DE) 2007-04-12 US disclosed
US-20070080343-A1 New materials for electroluminescence and the utilization thereof MERCK PATENT GMBH (DE) 2007-04-12 US disclosed