SCHEMBL31296445

SCHEMBL31296445

Cc1ccc(P(=O)(c2ccc(C)cc2)c2ccc3ccccc3c2-c2c(O)ccc3ccccc23)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.46
KDM4E B2RXH2 2/20 0.46
POLB P06746 1/20 0.46
RRM1 P23921 2/20 0.43
HKDC1 Q2TB90 2/20 0.43
KMT2A Q03164 4/20 0.41
MEN1 O00255 3/20 0.41
KDM4A O75164 1/20 0.39
CTDSP1 Q9GZU7 1/20 0.39
KDM4C Q9H3R0 1/20 0.39
NSD2 O96028 1/20 0.38
OPRM1 P35372 1/20 0.38
OPRD1 P41143 1/20 0.38
NPC1 O15118 2/20 0.38
RAB9A P51151 2/20 0.38
PTPN22 Q9Y2R2 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
TDP1 Q9NUW8 1/20 0.37
THRB P10828 1/20 0.36
ERN1 O75460 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10710567 0.91 MAPT (0.39) MAPTKDM4EPOLBRRM1HKDC1
SCHEMBL12336891 0.88 MAPT (0.43) MAPTKDM4EPOLBHKDC1KMT2A
SCHEMBL4403131 0.88 MAPT (0.43) MAPTKDM4EPOLBHKDC1KMT2A
SCHEMBL7025867 0.88 KMT2A (0.42) MAPTKDM4EPOLBRRM1HKDC1
SCHEMBL4401115 0.88 MAPT (0.43) MAPTKDM4EPOLBHKDC1KMT2A
SCHEMBL7591355 0.88 MAPT (0.43) MAPTKDM4EPOLBRRM1HKDC1
SCHEMBL7808240 0.85 MAPT (0.51) MAPTKDM4EPOLBRRM1HKDC1
SCHEMBL11991107 0.81 KCNJ11 (0.39) MAPTKDM4EPOLBKMT2AMEN1
SCHEMBL11991074 0.81 TDP1 (0.49) MAPTKDM4EPOLBKMT2AMEN1
SCHEMBL17747337 0.79 HKDC1 (0.32) MAPTKDM4EPOLBHKDC1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119219681-A Method for synthesizing axial chiral organoboron compounds 合成化学暨分子生物学有限公司 2024-12-31 CN disclosed